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2009 NOV 16 ... prognosis. Its elevated serum levels might be the result of pathological hyperplasia of myofibroblasts and smooth muscle cells together with deeper tumor invasion into muscle layers," wrote ...
2009 NOV 9 ... that primary renal epithelial cells from XOR-/- mice are more readily transformed to myofibroblasts, which is a marker of increased epithelial mesenchymal transition. These results suggest ...
2009 NOV 2 ... Current study results from the report, 'Targeting myofibroblasts in model systems of fibrosis by an artificial alpha-smooth muscle-actin promoter ...
2009 NOV 23 ... stem cells reside within a special 'niche' comprised of intestinal sub-epithelial myofibroblasts that tightly control their function. It has been postulated that mutations within these ...
2009 NOV 10 ... cells. We studied the quantification and the localization of MCs and myofibroblasts in NPs." "We examined NPs from 12 patients with chronic rhinosinusitis ...
2009 NOV 2 ... Here we report a role for the NOX4 isoform in tissue repair functions of myofibroblasts and fibrogenesis. Transforming growth factor. beta 1 (TGF-beta 1) induces NOX-4 ...
2009 NOV 16 ... "Diabetic nephropathy is the leading cause of chronic renal failure. Myofibroblasts play a major role in the synthesis and secretion of extracellular matrix in diabetic ...
2009 NOV 9 ... of epithelial genes and EMT inhibitors but induced genes that are expressed by myofibroblasts. Cyclopamine reversed these effects. in mouse NAFLD models, Hh-pathway activation, EMT, ...
2009 NOV 23 ... in UC, the present study focused on heterogeneous phenotypes of subepithelial myofibroblasts and interstitial cells, in association with mucosal remodeling," scientists in ...
2009 NOV 2 ... tissue tumor cells that are histogenetically related to activated fibroblasts and/or myofibroblasts, irrespective of their malignancy," wrote O. Dohi and colleagues, Tohoku University, ...
2009 NOV 1 ... receptor (PPAR)gamma, resulting in transdifferentiation of lung lipofibroblasts to myofibroblasts, i.e., the conversion of the lipofibroblast phenotype to a cell type that is not ...
2009 NOV 23 ... which kills macrophages. Sham-operated myocardium contained some sympathetic axons, few myofibroblasts and T cells and no CD-68-positive macrophages. In rats receiving saline liposomes ...
2009 NOV 16 ... of S100A4-positive fibroblasts were derived from bone marrow at this same time point. Myofibroblasts rarely derived from EMT or bone marrow progenitors. Both EMT and bone marrow progenitors ...
2009 NOV 2 ... when engaged in fibrogenesis, display the highly activated phenotype characteristic of myofibroblasts. These cells arc present in a large number in sites with ongoing inflammation, ...
2009 NOV 16 ... TGF-beta expression, increased levels of extracellular matrix components and activated myofibroblasts, accompanied by decreased Smad7 expression and increased Smad2/3 activation. In rats ...
2009 NOV 16 ... as well as immunostaining for cell-type-specific markers to quantify fibroblasts, myofibroblasts, and smooth-muscle cells. were compared with reference control mice processed in die ...
2009 NOV 1 ... daily to both control and experimental groups. alpha-Actin staining was used to identify myofibroblasts in the neointima. Lesions in B-cell-deficient B6 mice were not significantly different ...
2009 NOV 16 ... cells (VICs). VICs are fibroblastic cells that can differentiate to form activated myofibroblasts, displaying increased alpha smooth muscle actin (alpha SMA) expression, contractility, ...
