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2009 NOV 26 ... "Oxidative stress plays a key role in the pathogenesis of age-related neurodegeneration, and the nonenzymatic production of 8-iso-prostaglandin F-2 alpha (8-iso-PGF(2 alpha)) ...
2009 NOV 23 ... that could be developed as a neurotherapeutic for stroke, brain injury, or chronic neurodegeneration. However, the TNFR ECD is a large molecule therapeutic that does not cross the ...
2009 NOV 23 ... Research report. "The present study investigated the progressive nature of neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine/probenecid (MPTPp) chronic mouse ...
2009 NOV 23 ... "Platelets play a crucial role during stroke, and the inflammatory reaction promotes neurodegeneration. von Willebrand factor (VWF), an adhesion molecule for platelets, is elevated in ...
2009 NOV 17 ... Pathology (Overexpression of Wild-Type Murine Tau Results in Progressive Tauopathy and Neurodegeneration. American Journal of Pathology, 2009;175(4):1598-1609). For additional ...
2009 NOV 17 ... 15-20 million individuals worldwide and causes a broad spectrum of diseases including neurodegeneration and leukemia. The scientific program included a breadth of HTLV research topics: ...
2009 NOV 23 ... pathways regulated by thiol disulfide oxidoreductase(s) have been implicated in the neurodegeneration seen in PD. Oxidation of thioredoxin leads to activation of apoptosis signal regulating ...
2009 NOV 23 ... not against this neurotoxicity in the MeA. Here we show that a single dose of KA induces neurodegeneration in the subnuclei of the MeA of rats with different degrees of intensity in males and ...
2009 NOV 23 ... data in the report 'Activity-dependent survival of neurons in culture: a model of slow neurodegeneration.' According to recent research from Rehovot, Israel, "Central neurons express ...
2009 NOV 23 ... growth factor and peroxiredoxin) were upregulated. One gene that promoted excitotoxic neurodegeneration (latrophilin-2) was downregulated. Two genes involved in glutamate (protein kinase ...
2009 NOV 29 ... research led d'Azzo and her colleagues to propose that the death of brain cells and neurodegeneration that strikes GM1-gangliosidosis patients is a two-step process. The investigators ...
2009 NOV 16 ... activation of endogenous NSCs may be effective in reversing or preventing age-related neurodegeneration in humans. STEM CELLS 2009;27:2044-2052." Blackmore and colleagues ...
2009 NOV 27 ... astrocyte dysfunction represent a new paradigm underlying the association of apoE4 with neurodegeneration."Zhong and colleagues published their study in the Journal of Biological ...
2009 NOV 23 ... New research, 'ApoE4-dependent Abeta-mediated neurodegeneration is associated with inflammatory activation in the hippocampus but not the septum,' is ...
2009 NOV 23 ... sites at the central nervous system (CNS) to interfere with both neuroinflammation and neurodegeneration," scientists writing in the Journal of Neural Transmission report. ...
2009 NOV 16 ... "Our study indicates that damage to lower motor neurons and TRAIL-mediated inflammatory neurodegeneration in the spinal cord contribute to MS pathology." Vogt and colleagues ...
