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2009 NOV 16 ... cervical dysplasia and in carcinoma. However, this large TMA study shows that HER2/neu oncoprotein expression and HER2/neu gene amplification overall are uncommon events in cervical ...
2009 OCT 20 ... cancers show constitutive or amplified expression of the transcriptional regulator and oncoprotein Myc, making Myc a potential target for therapeutic intervention. Here we report the ...
2009 NOV 9 ... that induces the rapid onset of T-cell lymphomas in poultry. The MDV-encoded oncoprotein Meq plays an important role in oncogenicity, as its deletion abolishes the ability of ...
2009 NOV 16 ... of oral preneoplastic lesion (OPL) is difficult to assess. Delta Np63 is an early oncoprotein associated with mucosal tumorigenesis," investigators in the United States report. ...
2009 NOV 9 ... is implicated in cancer development and metastasis." "In contrast, the oncoprotein cyclin D1 inhibits anoikis. We further show that cyclin D1 interacts with FOXO proteins ...
2009 NOV 1 ... According to recent research from the United States, "ErbB2, a metastasis-promoting oncoprotein, is overexpressed in similar to 25% of invasive/metastatic breast cancers, but in ...
2009 NOV 2 ... viral protein. Thus, small artificial proteins that bear little resemblance to a viral oncoprotein can nevertheless productively interact with the same cellular target," wrote K. ...
2009 NOV 9 ... (mutant p53) cells. Inhibition of p53 was achieved in U87MG cells transfected with E6 oncoprotein (U87MG-E6) and treated with pifithrin-alpha, a reversible inhibitor of p53 (U87MG-PFT). ...
2009 NOV 2 ... acquired drug resistance. We hypothesized that switching off the crucial chimeric oncoprotein FIP1L1-PDGFRalpha on which HES cells depend, should have deleterious effects on the ...
2009 NOV 9 ... derivative (NC2213). In addition, phosphorylation of Src, a myristoylated oncoprotein was significantly decreased by 1.0 mc M of NC2213 as revealed by Western blot analysis. ...
2009 NOV 16 ... that coordinate polymer dynamics such as the microtubule-destabilizing protein stathmin (oncoprotein 18). In cancer cells, increased microtubule turnover affects cell morphology and ...
2009 NOV 2 ... The researchers concluded: "Our results suggest that FOXG1 acts as an oncoprotein inhibiting TGF-beta-mediated anti-proliferative responses in ovarian cancer cells ...
2009 NOV 23 ... factor c-Myc with aggressive behavior of many solid tumors. Therefore, this oncoprotein was evaluated as a prognostic marker for overall and metastasis-free survival in ...
2009 NOV 2 ... in cells without t(4;14) -and hence without high expression of MMSET, the ubiquitous oncoprotein in MM cells with t(4;14)," wrote T.K. Vatsveen and colleagues, Norwegian University of ...
2009 NOV 1 ... of Health. The researchers concluded: "Thus, tensin-3 is implicated as an oncoprotein regulated by Src and possessing an SH2 domain with a previously undescribed mechanism ...
2009 NOV 2 ... levels of p21(WAF1), p16(INK4), and p27(KIP1) proteins; and diminished levels of E7 oncoprotein. In contrast, normal keratinocytes that were infected with AAV2 or transfected with the ...
2009 OCT 19 ... "The human papillomavirus (HPV) 16 E7 oncoprotein has been reported previously to stimulate DNA damage and to activate host cell DNA ...
2009 NOV 16 ... The researchers concluded: "Our data establish FBP1 as an important oncoprotein overexpressed in HCC that induces tumor propagation through direct or indirect ...
