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2009 NOV 9 ... Medicine, Adolescence, Alcoholism, Behavior, Diagnostics, Mental Health, Neurology, Opioid Receptors, Psychiatric, Psychiatry. This article was prepared by Pain & Central ...
2009 NOV 23 ... These GI effects, which do not resolve over time, occur when opioids bind to mu-opioid receptors in the gut, reducing gastrointestinal motility and secretions. The consequences are not ...
2009 NOV 9 ... Modulators Opioid modulators can act as antagonists, agonists or partial agonists at opioid receptors throughout the body. Emerging biological research and new medicinal chemistry insights ...
2009 NOV 9 ... "The opioid peptide H-Tyr-c[D-Cys-Phe-Phe-Cys]NH2 cyclized via a methylene dithiother is a potent ... delta opioid agonist potency and showed only slight or no preference for mu over delta receptors. As expected, the six Dhp(1)- and (2S)-Mdp(1)-dicarba analogues turned out to be mu ...
2009 NOV 9 ... research from the United States, "Dynorphin A (Dyn A) is an endogenous ligand for K opioid receptors. To restrict the conformational mobility, we synthesized several cyclic Dyn A-(1-11)NH2 ...
2009 NOV 23 ... the cellular sites of interaction between agonists of N-methyl-D-aspartate (NMDA) and p-opioid receptors (mu OR) in the CeA are unknown," investigators in the United States report. ...
2009 NOV 9 ... According to recent research from Szeged, Hungary, "Several data suggest that both opioid and N-methyl-D-aspartate (NMDA) receptors are localized at the peripheral level, and ...
2009 NOV 9 ... confirms that the phenol component in opioids is essential for higher binding to the opioid receptors," wrote F.Y. Li and colleagues. The researchers concluded: "The different ...
2009 NOV 9 ... and duration of morphine antinociceptive activity via both alpha(2)-adrenergic and opioid receptors," wrote V.L.A. Pettersen and colleagues, Federal University. The ...
2009 NOV 9 ... Research, Hyperalgesia, Morphine, Narcotic, Neurochemistry, Neurology, Opiate Agonist, Opioid Receptors, Phospholipase, University of Siena. This article was prepared by Pain & ...
2009 NOV 16 ... dopamine-deficient still responded with aversions. When scientists inactivated the kappa opioid receptors involved in the serotonin system in the dorsal raphe nucleus -- the serotonin-abundant ...
2009 NOV 16 ... of Biological Chemistry (Purification and Functional Reconstitution of Monomeric mu-Opioid Receptors ALLOSTERIC MODULATION OF AGONIST BINDING BY G(I2). Journal of Biological Chemistry, ...