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2009 JAN 12 ... expression was dependent on a protein kinase C alpha/c-Jun-NH2-kinase 2/c-Jun signaling pathway activated by perifosine through reactive oxygen species production. Perifosine also ...
2009 NOV 1 ... Program, could lead to the development of new therapies that target the cell signaling pathway regulated by PTEN. A novel mouse model of neurofibromatosis type 1 (NF1) developed at ...
2009 MAR 10 ... through a novel regulatory cascade involving the activation of the P13K/Akt/Forkhead pathway."
Cabodi and colleagues published their study in the Journal of ...
2009 JUL 20 ... to recent research from the United States, "The mammalian target of rapamycin (mTOR) pathway may constitute a potential target for the treatment of malignant peripheral nerve sheath ...
2009 AUG 31 ... "Supporting the view that PTEN and PIK3CA act in the same P13K signaling pathway, genetic alterations in the PIK3CA and PTEN genes were mutually exclusive, except in one ...
2009 JAN 20 ... TNF alpha promoter. These results, together with our previous studies of the P13K/Akt pathway, demonstrate that wear particles coordinately activate multiple signaling pathways and ...
2009 JUN 22 ... response was controlled by the phosphatidylinositol 3-kinase (P13K)-Akt-signaling pathway, which normally regulates autophagy in response to nutrient availability," wrote S. ...
2009 OCT 12 ... in colon cancer cells. The phosphatidylinositol-3-kinase (PI3K)/protein kinase B (Akt) pathway is crucial for cell proliferation and survival," researchers in Lund, Sweden report. ...
2009 JUN 15 ... cytoprotection was associated with Akt phosphorylation and abrogated when the P13K/Akt pathway was inhibited. Comparable cytoprotection was also seen in experiments comparing ...
2009 MAR 2 ... improve cardiac function and remodeling via eNOS production associated with the P13K-Akt signaling pathway, Rho-kinase (ROCK) pathway, and the development of oxidative stress in ...
2009 MAY 25 ... to the janus kinase (JAK)/signal transducers and activators of transcription (STAT) pathway."
"Here, we report that HIV-1 gp120 protein activated STAT1 and ...
2009 MAY 25 ... for endothelial cell cord formation. Furthermore, lenalidomide inhibited VEGF-induced P13K-Akt pathway signaling, which is known to regulate adherens junction formation. We also found a ...
2009 JAN 20 ... TGF-beta 1-induced Cx43 gene expression demonstrating the involvement of c-Jun/AP-1 pathway together with p38 and P13K/AKT pathways in mediating TGF-beta 1-induced Cx43 gene ...
2009 JAN 6 ... factors, the key regulators of cell survival, are negatively controlled through the P13K-Akt signaling pathway. Phosphorylation of FOXO by Akt leads to cytoplasmic localization and ...
2009 AUG 3 ... the pseudopodia formation by thymosin beta 4 is probably involved in P13K and Rho family pathway. We recently reported that thymosin beta 4 expression is upregulated by androgen ...
2009 MAR 16 ... modulate the protein kinase B/phosphatidylinositol 3-kinase (Akt/PI3K) signaling pathway. Virology, 2009;383(1):78-85).
For additional information, contact M. ...
2009 JAN 5 ... to a study from Zurich, Switzerland, "The phosphoinositide 3-kinase (PI3K)/Akt pathway is frequently activated in human cancer and plays a crucial role in medulloblastoma ...
2009 JAN 19 ... Physiology (BMP-2 Increases Migration of Human Chondrosarcoma Cells Via P13K/Akt Pathway. Journal of Cellular Physiology, 2008;217(3):846-855).
Additional ...
2009 FEB 16 ... SHIP2 PDR/AAA promoted ubiquitination of the PDGFR and its degradation via the lysosomal pathway independently of the association between the E3 ubiquitin ligase c-Cbl and PDGFR," ...
