Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Google 2009 PageRank: #2 Among Top Health News and Media Publications
Google 2009 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2009 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2009 PageRank: #2 News and Media Site for the Pharmaceutical Industry
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
2009 OCT 19 ... of new antibiotic agents. We investigated the effect induced in the insect antimicrobial peptide apidaecin Ib by the replacement of a single arginine/leucine residue witha N-substituted ... 1155 16th St., NW, Washington, DC 20036, USA. Keywords: Italy, Padua, Antibiotics, Antimicrobial Resistance, Antimicrobials, Cytotoxic Activity, Drug Development, Drug ...
2009 NOV 23 ... of tRNA(Asp) by aspartyl-tRNA synthetase (AspRS). Changing the last residue of the McC peptide should result in antibacterial compounds with targets other than AspRS. However, ... USA. Keywords: City:Piscataway, State:NJ, Country:United States, Antibiotics, Antibacterial, Antibiotic, Antimicrobial, Enzymes, Escherichia coli, Synthetase, ...
2009 OCT 12 ... genetic modifications such as antibiotic resistance, biofilm formation, antimicrobial peptide resistance and pro-inflammatory lipid A structures. Lipid A is a component of the ... 16 Procter Street, London WC1V 6 Nx, England. Keywords: North Ireland, Antibiotics, Antimicrobial Resistance, Antimicrobials, Autosomal-recessive Disease, Biochemical, ...
2009 NOV 16 ... strain G27; four of these sequences had growth-inhibitory and bactericidal effects. The peptide with the highest efficacy against strain G27, C12K-2 beta(12), was selected for further ... gastric pathogen Helicobacter pylori has developed resistance to virtually all current antibiotics; thus, there is a pressing need to develop new anti- H. pylori therapies. The goal of ...
2009 NOV 23 ... multi-trajectory all-atom MD simulations to investigate the interactions of the peptide IL with model membranes. The lipid bilayer formed by the zwitterionic ... attracted much interest in recent years because of their potential use as new-generation antibiotics. Indolicidin (IL) is a 13-residue cationic AMP that is effective against a broad ...
2009 NOV 2 ... a bacterial (Escherichia coli) A-site rRNA model was chosen as a target to screen for peptide binders. Two heptapeptides, HPVHHYQ and LPLTPLP, were selected through M 13 phage ... According to a study from the United States, "For almost five decades, antibiotics have been used successfully to control infectious diseases caused by bacterial ...
2009 NOV 1 ... bacterial strains. The B. subtilis albB mutant that does not produce a putative immunity peptide was more sensitive to both subtilosin A and subtilosin A1. A spontaneous suppressor ... USA. Keywords: United States, Beaverton, Antibacterial Activity, Antibiotics, Antimicrobial Resistance, Antimicrobials, Drug Resistance, Hematology, Hemolytic, ...
2009 NOV 23 ... of antibacterials with a novel mode of action. This enzyme cleaves off the signal peptide from secreted proteins, making it essential for protein secretion, and hence for ... 233 Spring Street, New York, NY 10013, USA. Keywords: Belgium, Leuven, Antibiotics, Antibacterial, Antibiotic, Antimicrobial, Antimicrobials, Drug Development, Enzymes, ...
2009 NOV 16 ... "LBM415 is an antibacterial agent belonging to the peptide deformylase inhibitor class of compounds. It has previously been shown to demonstrate ... in sepsis and specific organ infection models irrespective of resistance to other antibiotics," wrote C.S. Osborne and colleagues. The researchers concluded: "Suggest ...
2009 NOV 16 ... belonging to the paracelsin family was isolated and characterized." "This peptide mixture was purified by column chromatography and preparative TLC on silica gel, and ... of bioactive secondary metabolites. From liquid culture a mixture of polypeptide antibiotics (peptaibols) belonging to the paracelsin family was isolated and characterized." ...
2009 NOV 23 ... Here we show that esculentin-1b(1-18) [Esc(1-18)] (GIFSKLAGKKLKN-LLISG-NH2), a linear peptide encompassing the first 18 residues of the full-length esculentin-1b, rapidly kills ... (Esculentin-1b(1-18) - a membrane-active antimicrobial peptide that synergizes with antibiotics and modifies the expression level of a limited number of proteins in Escherichia coli. ...
2009 NOV 9 ... charges. The present work reports the purification and characterization of a novel plant peptide with molecular mass of 5340 Da, named Cp-AMP, from seeds of C. pallida, a typical plant ... expressive increase of economical losses caused by fungi and resistant bacteria toward antibiotics. In order to find a solution to this problem, several studies have been concentrating on ...
2009 OCT 19 ... "We previously showed that a 20-residue basic peptide. N-WASP181-200 (NISHTKEKKKGKAKKKRLTK), inhibits renal accumulation of aminoglycoside ... N-WASP181-200 (NISHTKEKKKGKAKKKRLTK), inhibits renal accumulation of aminoglycoside antibiotics such as gentamicin and arbekacin," scientists in Japan report. "The aim ...
