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2009 NOV 1 ... intervention. Early diagnosis can, for certain cardiac conditions, allow for early pharmacologic treatment, which can prevent severe disease and costly, painful interventions later. The ...
2009 OCT 5 ... pressure quickly in hypertensive emergencies. Physicians should be familiar with the pharmacologic and clinical actions of drugs in treating hypertensive emergencies," wrote C.V. Ram and ... can be successfully treated, and complications can be largely prevented with timely intervention." Ram and colleagues published their study in Current Hypertension Reports ...
2009 AUG 31 ... "The goal of asthma therapy is to control symptoms using minimal pharmacologic intervention. To evaluate the efficacy and tolerability of once-daily budesonide/formoterol vs ...
2009 SEP 14 ... 3 to 6%. Only 16.3% of people with prior diagnosis of diabetes and who were receiving pharmacologic treatment, were in good glycaemic control (fasting glucose <6.1 mmol/l). The ... of diabetes and impaired fasting glucose is high in seven major Latin American cities; intervention is needed to avoid substantial medical and socio-economic consequences," wrote J. ...
2009 SEP 14 ... number of PTSD-focused studies presented at the MHRF evaluate the effectiveness of both pharmacologic and alternative treatment options. Topics examined include employing virtual ... Reed Army Medical Center is testing the effectiveness of the psychiatric service dog intervention for soldiers and veterans who are disabled by PTSD as well as the feasibility of ...
Subject: US Department of Defense Congressionally Directed Medical Research Programs
2009 SEP 28 ... groups. An interaction between interventions was observed such that, compared with no pharmacologic intervention, those allocated to insulin alone had a significant attenuation of inflammation ...
2009 NOV 23 ... facilitated tau degradation at lower doses, suggesting that we can combine genetic and pharmacologic manipulation of Hsp70 to control the fate of bound substrates. Disease relevance of this ... researchers concluded: "These findings reveal an entirely novel path toward therapeutic intervention of tauopathies by inhibition of the previously untargeted ATPase activity of Hsp70." ...
2009 OCT 12 ... characterization in preclinical models to identify the compound with the appropriate pharmacologic, toxicologic and pharmacodynamic profile for human clinical trials. Repligen licensed ... identifies histone deacetylase 3 (HDAC 3) as an important enzyme target for therapeutic intervention in Friedreich's ataxia. These research findings confirm the drug target of the HDAC ...
2009 OCT 26 ... The researchers concluded: "This study shows that improved performance after a pharmacologic intervention known to activate PDC was accompanied by an enhanced IL-6 response and a limited ...
2009 NOV 9 ... therapy resistant (MDA-MB-231) and chemoresistant (MCF-7TN-R) breast cancer cells. Pharmacologic intervention using these ceramide analogues inhibited clonogenic survival and induced apoptosis, with ...
2009 NOV 10 ... JHF lesions provide further understanding Of JHF pathogenesis and may offer a target for pharmacologic intervention to treat the skin lesions associated with JHF. (J Am Acad Dermatol 2009;61:629-38.)." ...
2009 SEP 14 ... kinases AXL and Fyn as well as CD44 and HMGA2. Small interfering RNA experiments and pharmacologic approaches identified FYN as a candidate for resistance to imatinib. Our findings ... and PD166326 resistance and identify Fyn as a new potential target for therapeutic intervention in CML," wrote S. Grosso and colleagues, INSERM. The researchers ...
2009 OCT 12 ... stress elicited by paraquat in DA cells, and it can serve as a novel target for pharmacologic intervention. Antioxid. Redox Signal. 11, 2105-2118." Cristovao and colleagues ...
2009 AUG 17 ... Gladstone Institute of Neurological Disease. The researchers concluded: "Pharmacologic targeting of the interactions of fibrinogen with its nervous system receptors could ... with its nervous system receptors could provide novel strategies for therapeutic intervention in neuroinflammatory and neurodegenerative diseases." Ryu and colleagues ...
2009 NOV 17 ... when RICM must be administered. The administration of N-acetylcysteine is a popular pharmacologic prophylaxis against CIN but its efficacy is unclear," wrote J.H. Ellis and colleagues, ... do not use RICM is the most direct way to avoid CIN. Hydration remains the bulwark of intervention when RICM must be administered. The administration of N-acetylcysteine is a popular ...
2009 AUG 17 ... or diabetes was identified. In this subset, patients were more likely to be on pharmacologic risk factor modification. Despite recommendations, the pharmacologic risk factor ... "The medical regimen of consecutive patients who presented for major vascular surgery intervention over 18 months was examined. Of the 325 patients identified, 176 (54%) were on ...
2009 AUG 13 ... sucrose did not differ. The current study was designed to assess the analgesic effect of pharmacologic (sucrose, water) and a non-pharmacologic measures (pacifier) in preterm infants and to ... (pacifier) in preterm infants and to find whether there is any synergism between these intervention in relieving pain during painful procedures." "In this double-blind, ...
2009 OCT 12 ... that TF is a common mediator of glomerular damage and a possible target for selective pharmacologic intervention," wrote S.V. Seshan and colleagues, Hospital for Special Surgery, Surgery Department. ...
2009 AUG 10 ... "Once an obese patient has failed attempts at diet modification, physical activity, pharmacologic treatment, and possibly even complementary and alternative therapies, the next step is ... depending on the individual's needs, comorbidities, and candidacy, a specific surgical intervention may be necessary. These procedures are restrictive, malabsorptive, and a combination of ...
