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2009 NOV 23 ... T cells show no significant differences of total and phosphorylated levels of ZAP70, phospholipase C gamma 1, and MAP kinases p38 and JNK but elevated baseline levels of MAP kinase ...
2009 NOV 16 ... about the regulation of eicosanoid synthesis proximal to the activation of cytosolic phospholipase A(2)alpha (cPLA(2)alpha), the initial rate-limiting step. The current view is that ...
2009 NOV 16 ... of SK1 attenuated thapsigargin-evoked calcium entry. Blocking S1P receptor 2 or phospholipase C attenuated calcium entry, whereas blocking S1P receptor 3 did not. Overexpression of ...
2009 NOV 23 ... feedback to mitral cells, causing disinhibition and Ca2+ influx. NE also activates phospholipase C (PLC) through alpha(1)-adrenergic receptors generating inositol 1,4,5-trisphosphate ...
2009 NOV 23 ... (xanthine/xanthine oxidase; XA/XO) on sperm ROS content, membrane lipid peroxidation, phospholipase (PL) A activity, and motility, viability, and capacitation was contrasted to ROS content ...
2009 NOV 23 ... product 9.5 (PGP 9.5) and chromogranin A (CgA) for endocrine cells, alpha-gustducin and phospholipase C beta 2 (PLC beta 2) as taste-signaling molecules, and cystic fibrosis transmembrane ...
2009 NOV 23 ... GPR54, which couples to the Gq isoform of G proteins, which in turn signal through the phospholipase C pathway." "Ligands for GPR54 are kisspeptins, which are peptides ...
2009 NOV 16 ... G beta gamma subunits freed from a pertussis toxin (PTX)-sensitive G-protein and phospholipase C (PLC) beta 4. A similar signalling mechanism is also partially responsible for ...
2009 NOV 16 ... research published in the Journal of Biological Chemistry, "The mammalian intracellular phospholipase A(1) (iPLA1) family consists of three members, iPLA(1)alpha/PA-PLA(1), iPLA(1)beta/p125, ...
2009 NOV 23 ... into acute myeloid leukemia (AML). Indeed, recent studies showed that phosphoinositide-phospholipase (PI-PL) Cbeta1 mono-allelic deletion correlates with a higher risk of AML evolution." ...
2009 NOV 16 ... Surrel and colleagues published their study in Molecular Pharmacology (Group X Phospholipase A(2) Stimulates the Proliferation of Colon Cancer Cells by Producing Various Lipid ...
2009 NOV 16 ... cells, binding experiments show that ETA is almost exclusively expressed and stimulates phospholipase C (PLC) activity and ERK1/2 phosphorylation and proliferation. In ELT3 cells, ETB is ...
2009 NOV 16 ... underlying signaling mechanisms involved through coadministration of inhibitors of phospholipase C (PLC), protein kinase C (PKC) or protein kinase A (PKA). Potassium-evoked ...
2009 NOV 16 ... calcium ion along with increased phosphorylation of spleen tyrosine kinase and phospholipase gamma 2. Additionally, Cd81(-/-) B cells responded to toll like receptor 4 stimulation ...
2009 NOV 24 ... clinically relevant concentrations. The ET sensitivity of TASK-1 required ETA receptors, phospholipase C, phosphatidylinositol 4,5-biphosphate, diacylglycerol, and protein kinase C in primary ...
2009 NOV 23 ... According to a study from Fukuoka, Japan, "Phospholipase C-related but catalytically inactive protein (comprising PRIP-1 and PRIP-2 [officially ...
2009 NOV 9 ... of 55 +/- 9% and 43 +/- 7%, respectively. It has been proposed that Ca2+-insensitive phospholipase A(2) (iPLA(2)) is involved in the activation of SOCE in many different cell types. The ...
2009 NOV 16 ... on several protein-and/or lipid-based mechanisms. Among the latter, we have studied the phospholipase A(2) (PLA(2))-mediated generation of wedge-shaped lysolipids, with the resulting local ...
2009 NOV 23 ... and lung damage. Recently, we discovered that the major cell-associated hemolytic phospholipase A(PlaB) shares no homology to described phospholipases and is dispensable for ...
