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2009 NOV 3 ... epigenetic silencing of the paternal X chromosome is erased. Epiblast identity and pluripotency were confirmed by contribution to chimaeras with germline transmission. These ...
2009 NOV 9 ... events. Regulation of these has been associated with germ cell-specific and pluripotency-associated transcription factors, but the role of general transcription factors (GTFs) ...
2009 NOV 10 ... in the journal Science, "Haploid embryonic stem (ES) cells combine haploidy and pluripotency, enabling direct genetic analyses of recessive phenotypes in vertebrate cells. Haploid ...
2009 NOV 16 ... study from Brno, Czech Republic, "The transcription program that is responsible for the pluripotency of human ESCs (hESCs) is believed to be comaintained by exogenous fibroblast growth ...
2009 NOV 23 ... "Central to the network hierarchy is a signature strikingly enriched for pluripotency-related genes. These genes are typically expressed in embryonic stem cells (ESCs), ...
2009 NOV 23 ... may reveal how signalling-induced epigenetic reprogramming may promote reacquisition of pluripotency." Bao and colleagues published their study in Nature (Epigenetic reversion ...
2009 NOV 16 ... Sheng Ding, PhD, The Scripps Research Institute discussing A Chemical Approach to Pluripotency and Reprogramming; Philip Avner, PhD, Institut Pasteur, France, on Developmental ...
2009 NOV 16 ... of 5.7%." "Targeted clone R-Olig2 (like the other clones) retained pluripotency, typical hESC morphology, and a normal parental karyotype 46,XY. Most importantly, GFP ...
2009 NOV 9 ... Nanog are master factors that also have unique characteristic ability of cell-specific pluripotency and self-renewal." "The expression of Nanog in fibroblasts confirms ...
2009 NOV 9 ... c-Myc-induced miRNAs into murine ES cells significantly attenuates the downregulation of pluripotency markers on induction of differentiation after withdrawal of the ES cell maintenance ...
2009 NOV 9 ... in Sao Paulo, Brazil report. "Tumor formation is also associated with the pluripotency of embryonic stem cells and may be induced as a consequence of complete ...
2009 NOV 2 ... France, "Oct4 exerts a dose-dependent dual action, as both a gatekeeper for stem cell pluripotency and in driving cells toward specific lineages. Here, we identify the molecular mechanism ...
2009 NOV 16 ... by treatment with an Ad vector containing the CA promoter, without a decrease in pluripotency or viability. We also found that the CA promoter had potent transduction ability in iPS ...
2009 NOV 9 ... (OCT4, SOX2, KLF4). T1D-specific iPS cells, termed DiPS cells, have the hallmarks of pluripotency and can be differentiated into insulin-producing cells," wrote R. Maehr and colleagues, ...
2009 NOV 2 ... characterization of their functions. In the present study, we show that LIN28, a pluripotency factor, is specifically expressed in undifferentiated spermatogonia (A(s), A(pr), and ...
2009 NOV 16 ... downregulation of Smad4, Wnt1, and PI3K expression by siRNA decreased the levels of pluripotency marker mRNAs of ESCs, including Oct4, Sox2, and FoxD3. Our results suggested that ...
2009 NOV 9 ... transcriptional regulator c-Myc (herein termed Myc), has a key role in stem cell (SC) pluripotency and tumourigenesis. Its deregulated expression contributes to cancer development and ...
2009 NOV 16 ... cells; however, there are persistent concerns that ex vivo-expanded CD34 cells may lose pluripotency and the ability to contribute meaningfully to long-term engraftment. To address this ...
