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2009 AUG 18 ... phyA, FHY1, FHL, LAF1, and HFR1 are components of protein complexes in vivo. In vitro pull-down assays demonstrated direct interactions between partner proteins with the N-terminal ... independently transmit phyA signals downstream of FHY1 and FHL. Coimmunoprecipitation experiments showed that phyA, FHY1, FHL, LAF1, and HFR1 are components of protein complexes in vivo. ...
2009 OCT 13 ... to regulate receptor function." "Here, using co-immunoprecipitation and pull-down experiments we showed a close and specific interaction between mGlu(5) receptor and NECAB2 in both ...
2009 AUG 10 ... by only 20 percent, compared with 200 percent in cells grown in low glucose. Similar experiments with diabetic and non-diabetic mice confirmed the findings: High glucose was ...
2009 OCT 12 ... targeted at the cell membrane, is partially glycosylated and still binds laminin in pull-down assays," wrote F. Sciandra and colleagues, Catholic University. The ... important for alpha-DG binding, namely F692 and F718. In this article, similar experiments performed on the alpha-DG C-terminal domain pinpointed two residues, G563 and P565, as ...
2009 SEP 7 ... with the conservation of the sequence of the I-helix among these different isoforms. Pull-down experiments indicated that all six 14-3-3 isoforms present in platelets bind to GPIbbeta. In ...
2009 AUG 17 ... of total cell extracts were affected by Hfq mutation or overexpression. Protein pull-down assay and co-immunoprecipitation experiments revealed that Hfq associated with ...
2009 OCT 15 ... combined. In support, Rp1L1 interacts with Rp1 in transfected cells and in retina pull-down experiments. Interestingly, photo-transduction kinetics are normal in single rods and whole retinas ...
2009 OCT 19 ... fragment of human Cul5 Was found to inhibit zinc-induced aggregation of HCCHp, and pull-down experiments revealed that zinc binding to HCCHp increases the strength of the HCCHp-Cul5 interaction ...
2009 NOV 2 ... between vaccinia and human proteins can be verified by independent methods using GST pull-down assays, representing a 63% validation rate for the Y2H hits examined (17/27)," wrote ... library will be a useful resource for future high-throughput functional proteomic experiments." Zhang and colleagues published their study in the Journal of Proteome ...
2009 OCT 19 ... PBF transfection compared with vector-only treatment. Coimmunoprecipitation and GST-pull-down experiments demonstrated a direct interaction between NIS and PBF, the functional consequence of ...
2009 NOV 27 ... desired biological effect: the ability to disrupt NOTCH function.Moreover, experiments in cultured cells as well as in mice proved the peptide's ability to limit the growth ...
2009 AUG 17 ... the cancer. Although Pride lost his life to the disease in 2004, his gift launched the experiments necessary to obtain NIH funding for the project. There are two main types ...
2009 JUL 20 ... as a major target for CIGB-300. In vivo, the CIGB-300-B23 interaction was shown by pull-down experiments and confirmed by the early in situ colocalization of both molecules in the cell ...
2009 AUG 25 ... long before dorsal closure starts. Quantitative analysis, combined with laser cutting experiments and simulations, reveals that tension-based dynamics and cell coupling control the force ...
2009 NOV 23 ... EWS protein in HEK cells occurs immediately after or even during translation. Pull-down experiments with recombinant EWS protein as bait, followed by mass spectrometric analysis identified ...
2009 SEP 29 ... to the apical cytoskeleton," scientists in the United States report. "Pull-down experiments using purified and recombinant proteins showed a complex of Hsp70 and atypical PKC on ...
2009 JUL 20 ... embarked upon a systematic search for interacting proteins. Glutathione-S-transferase pull-down assays combined with mass spectrometry led to the identification of the 70-kDa heat ... shock cognate protein (Hsc70) as a VMAT2 interacting protein. Co-immunoprecipitation experiments in brain tissue and heterologous cells confirmed this interaction. A direct binding was ...
2009 SEP 28 ... high in oocytes and early embryos but is low in blastocysts. A glutathione S-transferase pull-down assay revealed that KPNA7 has a strong binding affinity for the nuclear protein ... protein nucleoplasmin 2 relative to that of other importin alphas. RNA interference experiments demonstrated that knockdown of KPNA7 in early embryos results in a decreased proportion ...
2009 NOV 17 ... bacterial antigen. Confirmation of the binding capacity of ERM protein was assessed by pull-down assay and ELISA using recombinant Hsc70 and ERM proteins. Ezrin was depleted using siRNA ... protein family, as a molecule associated with Hsc70. Mouse TG cells were employed in all experiments, and B. abortus was used as the bacterial antigen. Confirmation of the binding capacity ...
