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2009 SEP 28 ... to TRISENOX in the phase 2 study of 40 patients with refractory or relapsed APL included QTc interval prolongation (n=16), APL differentiation syndrome (n=3), hyperleukocytosis ...
2009 OCT 19 ... In clinical trials, a small increase (2.8 msec) in the average change from baseline in QTc was observed at 45 minutes. These QTc prolongations ...
2009 SEP 21 ... to recent research from Rotterdam, Netherlands, "Thyroid free T4 is associated with QTc-interval prolongation, which is a risk factor for sudden cardiac death (SCD). ...
2009 SEP 28 ... the United Kingdom report. "Patients had CEA of 10 to 1,000 mu g/L, QTc <= 450 ms, no cardiac arrhythmia/ischaemia, and adequate hematology/biochemistry. ...
2009 OCT 19 ... in-hospital initiation of dofetilide (two with torsade de pointes, one with excessive QTc prolongation) and were not continued on this therapy. The remaining 17 were discharged ...
2009 NOV 23 ... to core labs. This solution extends the technology capabilities for ECG and QT/QTc studies conducted in PAREXEL's other early phase units worldwide, including sites ...
2009 NOV 16 ... adjustment for LVMI, Lown's score (>or=or <3), age (>or=or <65 years), and QTc max (>or=or <437 ms)," wrote S. Dimopoulos and colleagues, University of Athens. ...
2009 OCT 12 ... this study, we investigated the effects of propofol or etomidate on the corrected QT (QTc) interval during ECT in patients with major depression. Fourteen unpremedicated American ...
2009 OCT 12 ... estimated. Clinical tolerability and clinical laboratory safety, including effect on QTc interval, were assessed. Non-compartmental estimations of C-max, AUC, t(max), t(1/2) and ...
2009 NOV 2 ... were mild-to-moderate and transient. Examination of serum potassium, blood glucose, QTc interval, pulse rate, and blood pressure raised no concern over the safety of ...
2009 SEP 14 ... (treatment visit). Changes in QRS interval (primary endpoint), heart rate (HR), PQ, and QTc (HR-corrected QT) intervals were assessed and compared between groups. Of the 108 ...
2009 OCT 12 ... According to recent research from Essen, Germany, "Corrected QT (QTc) prolongation is predictive of cardiovascular mortality in both the general and human ...
2009 OCT 19 ... Ventricular hypertrophy was found in the LV, S, and RV, in association with dispersed QTc and oxidative stress in ISO-treated rats. mRNA and protein expression of MMP-9, PKC ...
2009 OCT 19 ... (r(2)=0.89 for heart rate, 0.83 for PR interval, 0.78 for QRS duration, and 0.89 for QTc). Recordings made by this patient-operated ECG device allow to detect arrhythmias and ...
2009 NOV 1 ... glucose, cholesterol, and triglycerides, blood pressure, heart rate, and ECG indexes (QTc, Cornell voltage-duration product, and rate-pressure-product). After a mean 65 months ...
2009 SEP 21 ... to analyze associations between toenail arsenic and QT and heart rate-corrected QT (QTc) durations and to examine effect modification by calcium channel blocker use, using ...
2009 SEP 14 ... of the few clues to the diagnosis. A 30-year-old woman presented with chest pain and a QTc of 525 ms," investigators in London, Canada report. "Four weeks later ...
