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2009 NOV 23 ... regulate transgelin expression. Reduction of CapG or transgelin expression in hPASMCs by RNA interference was accompanied by significantly impaired migration ability in vitro, especially under ...
2009 NOV 23 ... "Short hairpin RNAs (shRNAs) capable of stably suppressing gene function by RNA interference (RNAi) can mimic tumor-suppressor-gene loss in mice," scientists writing in the journal ...
2009 NOV 24 ... expression in ovaries and to examine the function of Bcl2l10 in oocyte maturation using RNA interference." "Bcl2l10 transcript expression was ovary and oocyte specific. Bcl2l10 ...
2009 NOV 23 ... glycosylation with a sub-phenotypic dose of tunicamycin, reduced single genes by RNA interference, and then sought loci where the combination caused a synthetic or dramatically enhanced ...
2009 NOV 23 ... and in the management of patients with this diease. Knockdown of hnRNP A1 expression by RNA interference led to the significant suppression of the cell growth in colorectal cancer SW480 cells ...
2009 NOV 23 ... ATM by both the pharmacological inhibitor caffeine and the specific small interferenceRNA (siRNA) rescued the G(2) arrest elicited by R16, indicating its ATM-dependent ...
2009 NOV 23 ... Exogenous SIRT1 expression repressed transcription, whereas knockdown of SIRT1 by RNA interference reversed this effect. IsoNAM decreased the level of mRNA for PEPCK-C but had no effect ...
2009 NOV 23 ... lithium, and was thus designated as Lithium-inducible SLC6 transporter or List. Either RNA interference (RNAi)-mediated knockdown or complete deletion of List resulted in a remarkable increase ...
2009 NOV 24 ... mice. The knockdown of PDGF receptor-alpha (PDGFRA) through lentiviral-mediated RNA interference reduces the growth of fSMCs and mSMCs in ex vivo cultures and in Matrigel implants. ...
2009 NOV 23 ... were decreased, whereas E-cadherin mRNA was increased when HDAC-2 was knocked down using RNA interference in NRK52-E cells. Interestingly, hydrogen peroxide increased HDAC-2 activity, and the ...
2009 NOV 23 ... Current study results from the report, 'A comparative study of transfection methods for RNA interference in bone marrow-derived murine dendritic cells,' have been published. According to a ...
2009 NOV 23 ... was immunocytochemically localized in the juxtanuclear Golgi. Knockdown of SPCA1 by RNA interference markedly delayed the differentiation in these cells. The cells retarded in ...
2009 NOV 23 ... stimuli were used to identify regulators of TIMP3 expression. SirT1 small interferenceRNA, cDNA, and TIMP3 promoter gene reporter were used to study SirT1-dependent regulation of ...
2009 NOV 23 ... on distinct aspects of endothelial cell behavior in vitro. Our experiments utilized RNA interference to establish cultured human endothelial cell lines with significant reduction of CLIC4 ...
2009 NOV 24 ... clones can be rescued by ectopic expression of a dominant negative form of Notch or by RNA interference (RNAi)-mediated repression of Notch. Conversely, overexpression of ph induces a ...
2009 NOV 23 ... cells sensitive to both IFN-alpha and IFN-gamma, only IFN regulatory factor 9 (IRF9)-RNA interference (RNAi) completely inhibited the antiproliferative activity of IFN-alpha among the ...
2009 NOV 23 ... and iNOS overexpression. Suppression of PKC beta(2) expression by small interferenceRNA decreased high-glucose-induced nuclear factor kappa B and extracellular signal-related ...
2009 NOV 23 ... treatments for respiratory syncytial virus (RSV) infections in children using Alnylam's RNA-interference (RNAi) technology. The RSV program also includes ALN-RSV01, for which ...
2009 NOV 24 ... characterized CCaMK (GI:195542474) from A. hypogea and downregulated the kinase through RNA interference (RNAi) to understand its role during organogenesis of its characteristic aeschynomenoid ...