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2009 SEP 22 ... (THE EFFECTS OF HYPEROXIA EXPOSURE ON LUNG FUNCTION AND PULMONARY SURFACTANT IN A RATMODEL OF ACUTE LUNG INJURY. Experimental Lung Research, 2009;35(5):380-398). ...
2009 OCT 5 ... "To explore the key genes involved in the development of liver cancer, we established a ratmodel induced by diethylnitrosamine to investigate the gene expression profiles of liver ... nodules, the early cancerous nodules and the cancerous nodules from the rats with lung metastasis were chosen to compare with liver tissue of normal rats to investigate the ...
2009 SEP 28 ... the administration of dobutamine decreases pulmonary edema and stimulates AFC in a ratmodel of lipopolysaccharide-induced lung injury. Adult male Sprague-Dawley rats were ...
2009 OCT 27 ... ventilation) with hypercapnia could be more protective than normocapnia, in a ratmodel of lung injury, we evaluated the effect of hypercapnic acidosis during HFOV," ...
2009 NOV 3 ... presented in the report 'Expression of cytokine-induced neutrophil chemoattractant in rat lungs by intratracheal instillation of nickel oxide nanoparticles.' According to recent ... neutrophil chemoattractant-1 (CINC-1), CINC-2alphabeta, and CINC-3) in the lung tissue and bronchoalveolar lavage fluid (BALF) were determined by quantitative ... nanoparticles by ultrasound diffusion and filtration, established an acute exposure model using animals, and examined inflammation and chemokine expression." "The ...
2009 OCT 19 ... of premetastatic niche preparation by exosomes.' "The metastasizing capacity of the rat pancreatic adenocarcinoma BSp73ASML (ASML(wt)) is strikingly reduced by a knockdown of ... medium (CM), strongly promote settlement of ASML(kd) cells in lymph nodes and lung. Fractionation of CM revealed a contribution by a soluble matrix and exosomes, where the ... (ASML(wt)) is strikingly reduced by a knockdown of CD44v4-v7 (ASML(kd)). We used this model to analyze the role of the CD44 variant isoform (CD44v) in (pre)metastatic niche ...
2009 SEP 21 ... published their study in Experimental Lung Research (EXTRACORPOREAL PHOTOPHERESIS IN A RATMODEL OF PULMONARY FIBROSIS. Experimental Lung Research, 2009;35(5):359-370). ...
2009 NOV 23 ... inoculation. Moderate replication of PRRSV was detected in primary cotton ratlung cell cultures, but no viral replication was detected following intranasal or ... vivo," scientists in Guelph, Canada report."To determine if a small animal model could be developed for PRRSV, 3 strains of laboratory rodent were examined for their ...
2009 SEP 28 ... HA) produced by HAS3 mediates LPS-induced lung injury in the mechanically ventilated rat and that milrinone (MIL), by blocking HAS3 mRNA expression, would prevent the injury. ... with a Phosphodiesterase 3 Inhibitor, Blocks Lung Injury in a Septic Ventilated Rat Model. Lung, 2009;187(4):233-239). For additional information, contact H. Mrabat, ...
2009 NOV 23 ... of combining simvastatin with a phosphodiesterase type-5 inhibitor, sildenafil, in the ratmodel of hypoxia-induced pulmonary hypertension. Rats were allocated to either: 1) a ... significantly endothelial nitric oxide synthase expression and cGMP levels in the lung and right ventricle above that produced by either drug independently and resulted in ...
2009 SEP 21 ... of MS80. The in vivo fibrotic efficacy was evaluated in a bleomycin instillation-induced ratmodel. We report that MS80, a new kind of sulfated oligosaccharide extracted from ... pulmonary fibrosis in vivo, as evidenced by improved pathological settings and decreased lung collagen contents," wrote H.D. Jiang and colleagues, Ocean University of China. ...
2009 SEP 21 ... dose with survival as endpoint. In cellular models, we studied AVE8134 on hypertrophy in rat cardiomyocytes, nitric oxide signaling in human endothelial cells (HUVEC) and LDL-uptake ... improved cardiac output, myocardial contractility and relaxation and reduced lung and left ventricular weight and fibrosis. In contrast, rosiglitazone exacerbated cardiac ... Pressure, Cardiology, Cardiomegaly, Cardiomyocyte, Coronary Artery, Drugs, Experimental Model, Fibrinolytic Agent, Fibrosis, Heart Failure, Hepatology, Hypertrophy, Hypoglycemic ...
2009 NOV 24 ... that a mutant unable to catabolize DL-alanine displays decreased competitiveness in a rat lung model of infection." Boulette and colleagues published their study in the ...
2009 NOV 3 ... CCL22 and the thymus activation-regulated chemokine CCL17 among chemokines, in a ratmodel of radiation pneumonitis/pulmonary fibrosis and preliminarily observed an increase ... "Idiopathic pulmonary fibrosis (IPF) is a chronically progressive interstitial lung disease of unknown etiology. Previously, we have demonstrated the selective upregulation ...
2009 SEP 28 ... in Comparative Medicine (Temporal Changes of Angiopoietins and Tie2 Expression in Rat Lungs after Monocrotaline-Induced Pulmonary Hypertension. Comparative Medicine, ... PH model. Histologic evaluation showed pathologic vascular remodeling in the arteries of lung sections 1 wk after monocrotaline treatment. Protein levels of Ang1, Ang2, eNOS, iNOS, ...
2009 OCT 20 ... "The aim of current study is to establish and evaluate a more adequate ratmodel of COPD. was performed with rats exposed to sidestream cigarette smoke 2 h/d and 7 ... 12, 24 and 36 wk in a CS chamber (carbon monoxide concentration was 231 +/- 11 ppm). The lung function was determined by using the forced oscillation technique. Pathologic changes ...
2009 OCT 12 ... apyrase APT102 attenuates lung graft injury in a cold ischemia reperfusion model of rat syngeneic orthotopic lung transplantation. Male Fisher 344 donor lungs were cold ...
2009 OCT 6 ... were investigated in LPS-induced acute lung injury (ALI) animal model (Sprague-Dawley rat) and through the in vitro studies. LPS-induced SICX was timely related to changes of ...
2009 OCT 12 ... be different. With the use of designed and purchased MMP/TIMP assays, investigation of rat MMP-2, 3, 714 and TIMP-14 mRNA expression was undertaken by Real Time PCR. The three ... published their study in Respiratory Research (MMP/TIMP expression profiles in distinct lung disease models: implications for possible future therapies. Respiratory Research, ... COPD. Despite this, the majority of reports only focus on single MMPs, often only in one model system." "This study aimed to investigate the profile of an extensive ...
