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2009 NOV 24 ... bone size and fracture risk were also assessed. rs143383 and three highly correlated singlenucleotide polymorphisms ( SNPs) in the GDF5 region were found to be independently ... "A polymorphism ( rs143383; T to C) near the GDF5 gene has been associated with height and ...
2009 NOV 23 ... Korean patients with SLE. Approximately 1.5 kb of CRP promoter region was screened for single nucleotide polymorphism (SNP) using direct sequencing and 3 SNP in CRP exons by restriction fragment length ...
2009 NOV 23 ... polymorphism and disease progression in chronic lymphocytic leukemia.' "A number of singlenucleotide polymorphisms (SNP) have been implicated to impact upon the disease course of ...
2009 NOV 23 ... using ELISA in patients with active untreated AOSD. Significantly lower frequencies of single-nucleotidepolymorphism -607/AA were observed in patients with AOSD compared to healthy ...
2009 NOV 24 ... The Q and q alleles were clearly distinguished by PCR-RFLP analysis at six conserved singlenucleotide polymorphisms in common wheat and wild and cultivated einkorn, emmer and ... we developed a method based on polymerase chain reaction - restriction fragment length polymorphism (PCR-RFLP) analysis. The Q and q alleles were clearly distinguished by PCR-RFLP analysis ...
2009 NOV 23 ... risk. There was no appreciable association with breast cancer risk overall for any single nucleotide polymorphism. For rs2854482 in AKR1C2, carrying 1 or 2 A alleles was associated with a 2.0-fold ...
2009 NOV 23 ... enzyme produced two fragments of 551 and 101 bp in exon 2-3 of IGFBP3 gene. Two singlenucleotide differences in IGF1 while six such differences in IGFBP3 gene existed in ... respectively. in 90 mithun (Bos frontalis). The PCR-RFLP analysis showed the absence of polymorphism in these fragments in the animals screened.""HindIII restriction enzyme ...
2009 NOV 23 ... patients with OLP and 99 unrelated healthy Japanese controls were genotyped for 14 singlenucleotide polymorphisms (SNPs) of genes that regulate host immune responses. Genotyping ... The researchers concluded: "These results suggest that TNFR2 +587 gene polymorphism may be associated with susceptibility to OLP." Fujita and colleagues ...
2009 NOV 23 ... "The aim of this study is to investigate the potential association between single-nucleotide polymorphisms (SNP) of XRCC1 codon 280 His and ERCC2 codon 751 Gln ... were studied by means of polymerase chain reaction (PCR) restriction fragment length polymorphism techniques," wrote X.D. Zhai and colleagues. The researchers concluded: ...
2009 NOV 24 ... data from all studies suggested a weak association of the C allele of the rs5744256 single nucleotide polymorphism on improving walking times in old age." Thomas and colleagues published ...
2009 NOV 23 ... necrosis and intracellular membrane accumulation. Genome-wide searching has yielded a single nucleotide polymorphism in the SLCO1B1 gene for the organic anion-transporting polypeptide that regulates statin ...
2009 NOV 23 ... 7 (rs3036811, Indel 7), an intron 5 SNP (rs33959637, IVS5-59), and a missense coding single nucleotide polymorphism (SNP) in exon 6 (rs3747531, P275A) in 136 nondiabetic Ashkenazi men under age 55 years ...
2009 NOV 23 ... case control study (297 vs 297) conducted in Chinese Hans, we investigated 4 tagging singlenucleotide polymorphisms (tSNPs), rs1805120, rs1036145, rs3807375, and rs2968857 in the ... are required to identify the etiological variants in linkage disequilibrium with this polymorphism. (J Cardiovasc Electrophysiol, Vol. 20, pp. 1158-1162, October 2009)." ...
2009 NOV 23 ... and glioblastoma. A correlation between methylation and the T allele of the rs16906252 single nucleotide polymorphism (SNP) in colorectal carcinomas has previously been reported," scientists writing in the ...
2009 NOV 23 ... We performed an association study to investigate the effect of putative functional singlenucleotide polymorphisms (SNPs) of BMP4 on development of cutaneous melanoma (CM)." ... of Cancer Research and Clinical Oncology (A predicted functional single-nucleotide polymorphism of bone morphogenetic protein-4 gene affects mRNA expression and shows a significant ...
2009 NOV 23 ... and explored whether they are confounded or modified by each other. Genotyping of tag singlenucleotide polymorphisms (SNPs) in the IRF4 gene was conducted in 990 NHL cases and 828 ... IRF4 rs12211228 and NHL and between hair and eye color and NHL. The IRF4 rs12203592 polymorphism (CT/TT genotype) was statistically significantly associated with eye color and ...
2009 NOV 23 ... from the United States, "There are conflicting reports about the significance of TCF7L2 single nucleotide polymorphism rs7903146, a single nucleotide polymorphism found to be ...
2009 NOV 23 ... presented in the report 'The ANKK1 kinase gene and psychiatric disorders.' "The TaqIA single nucleotide polymorphism (SNP, rs1800497), which is located in the gene that codes for the putative kinase ANKK1 ...
2009 NOV 23 ... cytokine playing a pivotal role in both innate and adaptive immune responses. A single nucleotide polymorphism located in the first intron of the human IFN-gamma gene can influence the secretion of ...
2009 NOV 23 ... use and physical inactivity, and is also influenced by allelic genotype of a polymorphic single nucleotide polymorphism (SNP) rs10757278 that is physically linked with the p16(INK4a) ORF," scientists writing ...
