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2009 AUG 10 ... remained lower in SLE patients than controls. CD4+ and CD8+ T-cell responses to staphylococcal enterotoxin B (SEB), which was used as a positive control, were normal in patients with ... are involved in the immune response to influenza; in SLE, antibody responses to the vaccine are diminished, but it is not known if the same effect is seen in cell-mediated ...
2009 MAR 23 ... the use of its proprietary MSCRAMM® protein technology to Wyeth for the development of staphylococcal vaccines.
Keywords: HIV/AIDS Co-Infection, AIDS, Acquired ... Viral Therapy, Virology, Inhibitex Inc.
This article was prepared by AIDS Vaccine Week editors from staff and other reports. Copyright 2009, AIDS Vaccine Week via ...
2009 JUL 6 ... with recombinant antigens. In mice challenged with bioluminescent S. aureus, reduced staphylococcal spread was measured by in vivo imaging. The recovery of S. aureus CFU from organs of ... Data detailed in 'Proteomics-based identification of anchorless cell wall proteins as vaccine candidates against Staphylococcus aureus' have been presented. "Staphylococcus ...
2009 JUL 13 ... efficient vaccine is as yet available. This serious threat drives extensive studies on staphylococcal physiology and pathogenicity pathways, especially virulence factors." ...
2009 JUN 29 ... in vitro T cell activation and expansion. We transferred the bacterial superantigen staphylococcal enterotoxin A (SEA) gene into B16 murine melanoma tumor cells, and used them to induce ... superantigen SEA in poorly immunogenic tumor cells can enhance their immunogenicity as a vaccine in vivo," wrote J.Y. Yu and colleagues.
The researchers concluded: "The ...
2009 JAN 19 ... the capsule or clumping factor A (ClfA) failed to protect the recipients against staphylococcal infections," investigators in Buenos Aires, Argentina report.
"We ... expressed under variable conditions, and this has complicated the design of an effective vaccine. Clinical trials that targeted the capsule or clumping factor A (ClfA) failed to protect ...
2009 MAR 31 ... States, "Methicillin-resistant Staphylococcus aureus is increasingly responsible for staphylococcal infections in the community. A large percentage of the community-acquired ... Researchers detail in 'The Panton-Valentine leukocidin vaccine protects mice against lung and skin infections caused by Staphylococcus aureus ...
2009 JUL 6 ... of pneumonia. Vaccine-based targeting of this toxin provides protection against lethal staphylococcal pneumonia in a murine model system, suggesting that a monoclonal antibody-based therapy ...
2009 MAR 30 ... a clinical benefit. Several novel antigens are being tested for potential inclusion in a staphylococcal vaccine, including cell wall-anchored adhesin proteins and exotoxins," wrote A.C. Schaffer ...
2009 JAN 26 ... clearly needed."
"Because many individuals who are susceptible to staphylococcal infections are not competent to mount an effective immune response, passive as well as ... as active immunisation strategies have been explored. A capsular polysaccharide-based vaccine (StaphVAX) showed promise in an initial phase III trial in haemodialysis patients, but ...
2009 FEB 24 ... "Staphylococcal enterotoxins (SEs) are the most common cause of foodborne diseases and toxic shock ... common cause of foodborne diseases and toxic shock throughout the world. However, no vaccine that prevents emesis induced by SEs has been described," researchers in Hirosaki, ...
2009 MAR 23 ... report.
"Few studies have evaluated vaccination of heifers against staphylococcal mastitis. The objectives of the present study were to evaluate the efficacy of a ... In a herd with a 3% prevalence of S. aureus IMI and a 30% prevalence of CNS IMI, the vaccine did not reduce the new staphylococcal IMI rate," wrote J.R. Middleton and colleagues, ...
2008 MAR 24 ... community-associated MRSA Preclinical development of vaccine candidates to prevent staphylococcal infections Efforts to improve diagnostics, particularly for healthcare-associated ...
2008 MAY 19 ... "This finding represents the first successful vaccine strategy for the treatment of staphylococcal pneumonia."
Deleo and colleagues published their study in the Journal of ...
2008 JUL 14 ... pathways expressed by chicken naive CD4(+) T cells, CD4(+) lymphocytes activated with staphylococcal enterotoxin B, and those malignantly transformed by Marek's disease virus,' new data ... CD4 (+) T cell proteomes," wrote J.J. Buza and colleagues, University of Saskatchewan, Vaccine and Infectious Disease Organization.
The researchers concluded: "While ...
2008 MAY 13 ... characterized by recurrent and often severe pulmonary infections, pneumatoceles, eczema, staphylococcal abscesses, mucocutaneous candidiasis, and abnormalities of bone and connective ... For additional information, contact D.C. Douek, NIAMSD, Human Immunology Sect, Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892, USA.
...
2008 MAY 19 ... generates antigen-specific immunoglobulin G responses and affords protection against staphylococcal pneumonia. Moreover, transfer of Hla-specific antibodies protects naive animals against ... Wardenburg and colleagues published their study in the Journal of Experimental Medicine (Vaccine protection against Staphylococcus aureus pneumonia. Journal of Experimental Medicine, ...
2008 MAY 26 ... According to a study from the United States, "Staphylococcal infections represent an enormous burden to the public health system in the US and ... to many antibacterials in a wide variety of staphylococcal strains, requires that vaccine development for staphylococcal diseases be re-evaluated. Finding a vaccine for ...
