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2009 FEB 9 ... esterification of 1-phenylethanol and vinyl acetate, the solubilized lipase showed high stereospecificity (ca. 99%) with a catalytic efficiency up to 56 nmol/(U h) with a high operational and ...
2009 AUG 10 ... of probe activation following pretreatment with a specific inhibitor of caspase-3. Stereospecificity was also exhibited by the lack of intracellular fluorescence upon administration of the ...
2009 AUG 3 ... dehydrogenase/reductase superfamily and shares the same phylogenetic origin. The stereospecificity of the hydride transfer from NAD(P)H within this superfamily is highly conserved, ...
2009 MAR 3 ... been determined. In the ex vivo experiments, only ABZ sulphoxidation was observed. The stereospecificity in ABZ sulphoxidation in vitro was slight, with preferential formation of (+)-ABZ.SO ...
2009 JUL 28 ... Fe-Pch. Docking experiments using the FptA structure and binding assays showed that the stereospecificity of Pch recognition by FptA was mostly due to the configuration of the siderophore chiral ...
2009 APR 27 ... suggested that Gly225 and Gly226 play an important role in determining the substrate stereospecificity of the enzyme," wrote U. Dhagat and colleagues, Monash University.
The ...
2009 JAN 26 ... in Czech Republic report.
"A 1149 (2007) 112-120] had described the stereospecificity of carbonyl reduction during phase I metabolic experiments in vitro. For in vivo ...
2009 JUN 15 ... another ThDP-dependent enzyme capable of catalyzing aldehyde condensation with high stereospecificity."
Brandt and colleagues published their study in Biochemistry ...
2009 FEB 2 ... P450s ( P450s) metabolize a large number of diverse substrates with specific regio- and stereospecificity. A number of compounds, including nicotine, cotinine, and aflatoxin B-1, are metabolites ...
2009 AUG 17 ... produces the erythro diastereomer of C beta-hydroxylated L-arginine. This unexpected stereospecificity is caused by conformational control of the bound substrate, which enforces a gauche(-) ...
2009 JUL 20 ... The researchers concluded: "However, the known exo > endo epoxide stereospecificity of the DNA alkylation is observed even with free deoxyguarrosine (ratio >20:1 ...
2009 JUN 15 ... stereoisomers. Rapid racemization of DHD catalyzed by Julong 732 prevented the substrate stereospecificity in the conversion of DHD into THD from being confirmed. The absolute configuration of ...
2009 FEB 10 ... by mutational analyses. We expected these residues to be involved in determining the stereospecificity of the P2Y(11) receptor. After mutation of Arg268 to alanine or glutamine, the ...
2009 MAR 3 ... for thiazolicline ring closure and contribute to product selectivity and high stereospecificity. A low-barrier pathway for P-lactam formation is found where the proton required for ...
2009 JUN 15 ... "d-3-Hydroxybutyrate dehydrogenase (HBDH) from Pseudomonas fragi showed a strict stereospecificity to the d-enantiomer of 3-hydroxybutyrate (d-3-HB) as a substrate. The l-enantiomer acts ...
2009 JUL 14 ... as measured by liquid chromatography-tandem mass spectrometry analysis. The stereospecificity was also decreased, as L384A formed the R and S isomers of 10-HPODE and 8-HPODE in a 3:2 ...
2009 SEP 21 ... pocket. Candidate orientations were refined based on known structure-activity and stereospecificity characteristics of BZDs and the impact of the alpha(1) H101R mutation. favor a model in ...
2009 APR 27 ... organelle and promoted further studies on PO. D-Amino acid oxidase catalyzes with strict stereospecificity the oxidative deamination of D-amino acids. The oxidase is significantly more active in ...
2008 NOV 3 ... Researchers detail in 'Kinetics, substrate specificity, and stereospecificity of two new protein tyrosine phosphatase-like inositol polyphosphatases from Selenomonas ...
2008 DEC 23 ... be a major determinant of binding of AMIC to acidic phospholipids. Despite the lack of stereospecificity, AMIC binds 10 times more strongly to vesicles containing 5% PIP2 plus 25% PS than to ...
