Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Google 2009 PageRank: #2 Among Top Health News and Media Publications
Google 2009 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2009 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2009 PageRank: #2 News and Media Site for the Pharmaceutical Industry
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
2009 NOV 23 ... ligand (APL), ARG301, in a Phase I study of Rheumatoid Arthritis patients. ARG301 is a synthetic peptide, which in animal studies appears to down regulate autoimmunity to Type II ... R&D approach." Research in animal models suggests APLs (Altered Peptide Ligands) are effective in preventing and ameliorating tissue-specific autoimmune diseases. ...
2009 NOV 2 ... combines world-renowned expertise from the University of Nottingham in the fields of synthetic chemistry and molecular pharmacology to produce high quality fluorescent receptor ... chemistry and molecular pharmacology to produce high quality fluorescent receptor ligands as key components in drug candidate screening assays and imaging techniques. This new ...
2009 NOV 16 ... gene transcription occurring via factors such as NF-kappa B. In the present study, the synthetic glucocorticoid, dexamethasone, induces expression of MKP-1 (mitogen-activated protein ... concluded: "GR transactivation is essential to the anti-inflammatory properties of GR ligands." King and colleagues published their study in the Journal of Biological ...
2009 NOV 17 ... of Pharmacology and Experimental Therapeutics (Functional Selectivity of Natural and Synthetic Prostaglandin EP4 Receptor Ligands. Journal of Pharmacology and Experimental ...
Subject: Pharmacology and Experimental Therapeutics
2009 NOV 24 ... dot 4H(2)O in H2O, in the absence of counterions, have been investigated. The synthetic study has led to the two new complexes [Ni(O2CMe)(2)(hmpH)(2)] (1) and ... by two 1.10 (Harris notation) MeCO2- groups and two N,O-chelating (1.11) hpmH ligands. The tetranuclear cluster molecule of 2.2.25H(2)O center dot 0.5(1,4-dioxane) possesses ...
2009 NOV 17 ... residue, usually in a consensus context R/KXXR/K. Phage expressing these sequences and synthetic nanoparticles coated with them bound to and were internalized into cells." ... of vascular permeability, and the development of the nervous system. VEGF-A165 and other ligands of NRP-1 possess a C-terminal CendR sequence that interacts with the b1 domain of NRP-1 ...
2009 NOV 24 ... ones from the hospital environment. The thermal behaviour steps were investigated in synthetic air flow. The thermal transformations are complex processes according to TG and DTA ... paper reports the investigation on the thermal stability of new complexes with mixed ligands of the type [Cd(NN)(C3H3O2)(2)(H2O)(m)]center dot nH(2)O [(1) NN: 1,10-phenantroline, m ...
2009 NOV 23 ... Zuber and colleagues published their study in Molecular Pharmaceutics (Synthetic Viruslike Particles for Targeted Gene Delivery to alpha(V)beta(3) Integrin-Presenting ... system. In this manuscript, we have decorated the nanometric particles with cyclic RGD ligands in order to target endothelial cells," wrote G. Zuber and colleagues, University of ...
2009 NOV 9 ... "Mono- and bis-indolomorphinans were synthesized through a multi-step synthetic approach from the alkaloid, thebaine, to further explore the C-ring SAR ... study in Chemical Biology & Drug Design (Synthesis and SAR Study of Opioid Receptor Ligands: Mono- and Bis-Indolomorphinans. Chemical Biology & Drug Design, 2009;74(4):335-342). ...
2009 NOV 2 ... mutated bacterial dehalogenase which is fused to the protein of interest--and a synthetic haloalkane ligand that contains a fluorophore or affinity tag. By using cell-permeable ... haloalkane ligand that contains a fluorophore or affinity tag. By using cell-permeable ligands of distinct fluorescence, it is possible to image distinct pools of newly synthesized ...
2009 NOV 2 ... binding of TgMIC1 to 2-3- and 2-6-linked sialyl carbohydrates. Interestingly, two novel synthetic fluorinated analogs of 3'SiaLacNAc(1-4) and 3'SiaLacNAc(1-3) were identified as highly ... T. gondii adhesive protein, TgMIC1, to bind to a wide spectrum of sialyl oligosaccharide ligands." "Here, we investigate by further microarray analyses in a dose-response ...
2009 NOV 27 ... "Combinatorial methods including stoichiometric treatments of dye with freshly synthetic manganese(IV) complex, utilization of radical scavenger, and intermediate analysis by ... (Decolorization of Dye Pollutions by Manganese Complexes with Rigid Cross-Bridged Cyclam Ligands and Its Mechanistic Investigations. Journal of Physical Chemistry a, ...
2009 NOV 16 ... receptor and describes for the first time this mutant as a receptor activated solely by synthetic ligands (RASSL), with a rich pharmacology," wrote D. Cussac and colleagues. The ...
2009 NOV 16 ... according to a model whereby ghrelin is a partial agonist with respect to each of the synthetic agonists tested." Bennett and colleagues published their study in ... as agonists at the ghrelin receptor and have been described as ''ago-allosteric'' ligands because of an ability to also modulate the maximum efficacy and potency of ghrelin ...
2009 NOV 24 ... Bucharest, Romania report."The thermal behaviour steps were investigated in synthetic air flow. The thermal transformations are complex processes according to TG and DTG ... "A series of new complexes with mixed ligands of the type RuL2(DMSO) (m) Cl-3 center dot nH(2)O ((1) L: norfloxacin (nf), m = 1, n = ...
