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2009 NOV 23 ... published in Nature, Drs. Bradner and Verdine showed in multiple models, including T-cell acute lymphoblastic leukemia (T-ALL), that Stapled Peptides achieved tight direct binding to the Notch transcription ...
2009 NOV 16 ... heavily pretreated patients with resistant and refractory CML and Philadelphia-positive acutelymphoblasticleukemia, including those with the T315I mutant variant of the target ...
2009 NOV 16 ... with imatinib-resistant and -intolerant CML and Philadelphia chromosome-positive acutelymphoblasticleukemia. Nilotinib, an analog of imatinib, more potent than its parent ...
2009 NOV 2 ... Scientists discuss in 'MEK inhibitors potentiate dexamethasone lethality in acutelymphoblasticleukemia cells through the pro-apoptotic molecule BIM' new findings in ...
2009 NOV 23 ... frequency of FLI-1 immunoreactivity in a series of ALL cases and an expanded series of T-cell lymphoma subtypes," researchers in the United States report. ... "of CD45-negative acutelymphoblastic lymphoma/leukemia (ALL) immunoreactive for CD99 and Friend Leukemia ...
2009 NOV 9 ... their study in Clinical Lymphoma & Myeloma (Therapeutic Targeting of NOTCH1 Signaling in T-Cell Acute Lymphoblastic Leukemia. Clinical Lymphoma & Myeloma, 2009;9(Suppl. 3):S205-S210). For additional ...
2009 NOV 16 ... 5 months after allogeneic bone marrow transplantation from an unrelated donor for acutelymphoblasticleukemia," scientists in Chiba, Japan report. "His renal ...
2009 NOV 27 ... is often damaged, or mutated, in patients with a form of blood cancer, known as T-ALL or T-cell acute lymphoblastic leukemia.Abnormal NOTCH genes found in cancer patients remain in a state of constant ...
2009 NOV 23 ... determinations for assessing compliance with maintenance therapy for childhood acutelymphoblasticleukemia,' is now available. According to recent research published in ...
2009 NOV 2 ... stem cell transplantation is a potential therapeutic approach for adults with high-risk acutelymphoblasticleukemia in remission: results of a prospective phase 2 study,' are ...
2009 NOV 9 ... has announced the addition of the "Stakeholder Insight: Acute Leukemias - Reaching the Limits of Cytotoxic Chemotherapy" report to their offering. ... offering. The drug therapy of acute myeloid leukemia (AML) and adult acute lymphoblasticleukemia (ALL) is largely based on chemotherapy regimens that have changed little in the ...
2009 NOV 16 ... to 80 percent overall. When St. Jude opened its doors in 1962, the survival rate for acutelymphoblasticleukemia (ALL), the most common form of childhood cancer, was 4 percent. ...
2009 NOV 9 ... (''hematogones'') from 75 specimens and on leukemic blasts in 45 newly diagnosed B-acutelymphoblastic leukemias (B-ALL) cases." "We found that the less mature ... CD34 on Normal Bone Marrow B-Cell Precursors (''Hematogones'') and B Lymphoblastic Leukemia Blasts. American Journal of Clinical Pathology, 2009;132(4):573-580). For ...
2009 NOV 9 ... According to recent research published in the journal Clinical Lymphoma & Myeloma, "T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) are considered the same disease, ...
2009 NOV 9 ... bone marrow microenvironment provides critical support for the growth and survival of acutelymphoblasticleukemia cells and protection against the effects of chemotherapeutic ...
2009 NOV 2 ... Kingdom, "We report 2 novel, cryptic chromosomal abnormalities in precursor B-cell acutelymphoblasticleukemia (BCP-ALL): a translocation, either t(X;14)(p22;q32) or ...
2009 NOV 2 ... Investigators publish new data in the report 'Interphase FISH on TEL/AML1 positive acutelymphoblasticleukemia relapses--analysis of clinical relevance of additional TEL and ...
