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2009 NOV 23 ... between pulmonary arteriovenous malformations (PAVMs) and MA in hereditary haemorrhagic telangiectasia (HHT)." "All 220 consecutive HHT patients who underwent high-resolution ...
2009 NOV 16 ... fashion that requires NER-generated, single-stranded repair intermediates and ataxia telangiectasia-mutated and Rad3-related protein. Our results reveal a conserved pathway of DNA ...
2009 NOV 17 ... "Tissue abnormalities were found in all investigated organs. Deterioration and telangiectasia of gill filaments were found. Liver tissue revealed hemorrhages, blood congestion and ...
2009 NOV 9 ... in Bonn, Germany conducted a study "To assess metamorphopsia in patients with macular telangiectasia (MacTel) type 2. In a prospective observational cohort study, 40 eyes of 20 patients ...
2009 NOV 23 ... in the United States report. "In the authors' hereditary hemorrhagic telangiectasia (HHT) center, all PAVM embolizations in teenagers and adults are performed in the ...
2009 NOV 23 ... and amonafide were revealed to induce phosphorylation of the DNA damage sensor ataxia telangiectasia-mutated (ATM) responding to DNA double-strand breaks (DSBs). Inhibition of ATM by both ...
2009 NOV 24 ... sections revealed no significant difference in the number of dermal blood vessels and telangiectasia between the areas studied. There were nine cases that showed one or more of the ...
2009 NOV 23 ... and induced DNA damage. Activation of checkpoint kinase (CHK) 1 and H2AX, but not ataxia telangiectasia mutated and CHK2, were observed. Furthermore, inhibition of p53 using pifithrin-alpha ...
2009 NOV 23 ... journal Breast Cancer Research and Treatment, "Blood relatives of patients with ataxia-telangiectasia (A-T) have an increased risk to develop breast cancer. Allelic heterogeneity has made it ...
2009 NOV 16 ... According to a study from the United States, "Ataxia-telangiectasia (A-T) is a genetic disorder caused by a mutation of the Atm gene, which controls DNA ...
2009 NOV 1 ... recommend presymptomatic coil embolotherapy for patients with hereditary hemorrhagic telangiectasia (HHT) who have pulmonary arteriovenous malformations (PAVNis), this approach has not ...
2009 OCT 26 ... diagnosis, in case of sequencing senataxin gene only in non-Friedreich ataxia non-ataxia-telangiectasia ataxic patients with AFP level >or=7 microg/l, is 0.23% and the probability for a ...
2009 NOV 23 ... over a 1-year review analysis in patients with type 2 idiopathic juxtafoveal retinal telangiectasia (MacTel). Nine eyes of 9 patients with MacTel underwent repeated scotopic and photopic ...
2009 NOV 23 ... According to a study from Toronto, Canada, "Hereditary haemorrhagic telangiectasia (HHT) is an autosomal dominant disease characterised by vascular dysplasia complicated ...
2009 NOV 3 ... divergent phenotypes are dependent on the activation, or lack thereof, of an ataxia telangiectasia and Rad3-related (ATR)-dependent S phase checkpoint that inhibits replication fork ...
2009 NOV 23 ... epithelium (score 2.36) (ANOVA, p<0.0001). In conjunction, activation of the ataxia telangiectasia mutated (ATM)-Chk2 checkpoint pathway was observed in all histological grades of PanIN ...
2009 NOV 16 ... the response of human ES cells to DNA damage, we investigated the function of the ataxia telangiectasia mutated (ATM) DNA damage signaling pathway in response to gamma-irradiation." ...
2009 OCT 13 ... canonical and alternative pathways, partly in a manner that is independent of the ataxia-telangiectasia mutated kinase (ATM)." "Silencing of Rad50 or CtIP decreases end-joining ...
2009 OCT 19 ... recombination (HR)dependent repair of DNA double strand breaks (DSBs) and ataxia telangiectasia-mutated (ATM)-mediated checkpoint pathways. Here we present evidence that hSSB2, a ...
