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2009 NOV 2 ... with TNF-related apoptosis-inducing ligand (TRAIL); taurodeoxycholic acid (TDCA); thapsigargin (TG), to induce cell apoptosis through death receptor-, mitochondria-, or ER-mediated ...
2009 NOV 16 ... procoagulant phosphatidylserine (PS) exposure. Platelets were stimulated with A23187, thapsigargin (TG) and thrombin plus convulxin (Thr/Cvx), and Jurkat cells with ionomycin, in the ...
2009 NOV 23 ... protein trafficking assessed using VSVG. This was not secondary to ER stress, since thapsigargin, which compromises chaperone function by depletion of ER calcium, markedly inhibited ...
2009 NOV 23 ... collagenase digestion and treated in culture with the apoptosis inducers staurosporine, thapsigargin, gamma-irradiation, proinflammatory cytokines, or Fas ligand. Cell death was assessed by ...
2009 OCT 19 ... but reduced its duration by 27 +/- 6%. Depletion of intracellular Ca2+ stores with thapsigargin prevented GnRH-induced increase in [Ca2+](i)....
2009 OCT 5 ... (ER) stress in the enhancing effect of SAHA on CDDP, compared with the ER stressor thapsigargin." "We chose OSCC cell line HSC-3 to ascertain the mechanism of ...
2009 NOV 1 ... leukemia cells and fluorometric imaging plate reader intracellular Ca2+ assays using thapsigargin-stimulated Jurkat T cells and its detailed selectivity profile defined using a range of ...
2009 NOV 10 ... calcium increase was significantly reduced. Neither calcium depletion, nor gadolinium or thapsigargin were able to inhibit the calcium accumulation," wrote B.H. Hou and colleagues. ...
2009 NOV 2 ... with Ca2+ clearance-inactivation of the endoplasmic reticulum Ca2+-ATPase with thapsigargin and inhibition of the plasma membrane Ca2+ ATPase with high pH-significantly accelerated ...
2009 OCT 5 ... According to a study from Innsbruck, Austria, "Thapsigargin is a pro-apoptotic chemical, which has been shown to be useful to study cell death of ...
2009 NOV 2 ... in murine fibroblast NIH3T3 cells in response to tunicamycin, brefeldin A (brefA), thapsigargin, and DTT that lead to accumulation of unfolded proteins within the ER," wrote V.M. ...
2009 NOV 30 ... concluded: "Calcium channel blocker verapamil (20 mc M), Ca2+-ATPase inhibitor thapsigargin (5 mc M), and general membrane stabilizer lidocaine (10 mM) partially attenuate ...
2009 NOV 24 ... from stores was blocked by ryanodine; in another, stores were partially emptied using thapsigargin plus caffeine, after which syntillas were decreased," wrote J.J. Lefkowitz and ...
2009 OCT 19 ... donor S-nitroso-N-acetyl-D, L-penicillamine (SNAP), with the effects of SERCA2 inhibitor thapsigargin (TG) on MAPK, nuclear factor kappa B (NF kappa B), Bcl-2 proteins, ER stress, and ...
2009 NOV 23 ... dramatically increases the sensitivity of cancer cells to the ER stress-inducing drug thapsigargin, and vice versa, demonstrating the first example of mechanism-based synergism in the ...
2009 NOV 30 ... resistance. Intracerebroventricular (ICV) administration of the ER stress inducer thapsigargin (TG) increased food intake and body weight. Furthermore, ICV or intra-hypothalamic ...
2009 NOV 9 ... a large number of compounds with biological activity. One of these guaianolides, thapsigargin from the genus Thapsia (Apiaceae), has been a subject of particular interest in recent ...
2009 OCT 20 ... release were induced by the sarcoendoplasmic reticulum Ca2+-ATPase (SERCA) inhibitor thapsigargin, accompanied by similar kinetics and intensity of ATF4 induction. sHA 14-1 directly ...
