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2009 APR 13 ... a custom human CGH 385K microarray consisting of 50bp long oligonucletide probes tiled across the 38Mb p-arm of chromosome 12, which enabled the characterization of chromosome ... instruments and services. Roche NimbleGen produces high-density arrays of long oligonucleotide probes that provide greater information content and higher data quality necessary for ...
2005 NOV 28 ... In both array formats, oligonucleoticle probes were of isothermal design and were tiled through genic and inter-genic regions."
The investigators wrote, ... of chromosome breakpoints in neuroblastoma at sub-kilobase resolution using fine-tiling oligonucleotide array CGH (oaCGH).
"Understanding the genes and genetic pathways ... in this study: a whole-genome array with a 6-kb median probe spacing and fine-tiling arrays for selected genomic regions with either 50- or 140-bp median probe spacing. In both ...
2005 MAY 9 ... The Human Whole-Genome Array CGH product is a single-array design with 385,000 probes tiled throughout the human genome with a median probe spacing of 6,000 bp, thus enabling the ... NimbleGen combines its high-capacity 385,000 probe microarrays with its long oligonucleotide probes designed with matched melting temperatures to produce the highest resolution ... number changes on the whole-genome level or at ultra-high resolution using fine-tiling arrays for selected chromosomal regions.
Array CGH is a widely used technique ...
2008 SEP 8 ... the current list of genes and improving the gene structure models using NimbleGen tiled expression arrays. The experimental results better delineate transcribed regions of the ... independent samples can be analyzed simultaneously on a single slide. With 135,000 long oligonucleotide probes per array, complete transcriptome coverage is achieved. Similar to the 385K and ...
2008 JUN 2 ... unique 50mer probes selected from 30 megabases of human sequence data. These probes are tiled, or spaced apart, every 38 bases, thus creating a 12-base overlap between probes, which ... protein-DNA interactions. This study revealed that microarrays employing longer oligonucleotide probes (50mers) are the most sensitive at detecting very low enrichment in simulated ... comparison of tiling microarray platforms showed the Roche NimbleGen ChIP-chip arrays for ENCODE (ENCyclopedia Of DNA Elements) studies to be the most sensitive platform ...
