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2009 NOV 23 ... Many viral gene products including EBNA1, LMP1, and LMP2 have been implicated in NPC tumorigenesis, although the de novo control of these viral oncoproteins remains largely unclear." ...
2009 NOV 23 ... as an important immune target and highlight its possible role in signal transduction and tumorigenesis in MGUS and MM. (Blood. 2009; 114:3276-3284)." Blotta and colleagues ...
2009 NOV 23 ... a transmembrane heparan sulfate proteoglycan, is a critical mediator in the tumorigenesis of colon carcinoma cells. We explored the function of syndecan-2 in melanoma, one of the ...
2009 NOV 23 ... between biological responses activated during psychosocial stress and mammary tumorigenesis," researchers in the United States report. "Experiments in mouse models ...
2009 NOV 23 ... "Dysregulated WNT signaling through beta-catenin is a well-established mechanism for tumorigenesis. We have developed a mouse model that expresses constitutively activated beta-catenin in ...
2009 NOV 23 ... "Tyrosine phosphorylation is important in signaling pathways underlying tumorigenesis. We performed a mutational analysis of the protein tyrosine kinase (PTK) gene family in ...
2009 NOV 27 ... Recent lab-based studies have sought to characterize the relationship between tumorigenesis and the induction of molecular defenses, such as heat shock ...
2009 NOV 23 ... According to recent research from the United States, "During mammary tumorigenesis, there is a profound thymic involution associated with severe depletion of the most ...
2009 NOV 23 ... United States, "Pten is a tumor-suppressor gene involved in stem cell homeostasis and tumorigenesis. In mouse, Pten expression is ubiquitous and begins as early as 7 days of gestation." ...
2009 NOV 23 ... novel therapies, suggesting the need for further identification of factors mediating tumorigenesis and drug resistance. Using both in vitro and in vivo MM xenograft models, we show that ...
2009 NOV 23 ... only epithelial but also stromal genetic instability possibly contributes to colorectal tumorigenesis. To assess the increasing risk of carcinogenesis in the colorectum with aging, we ...
2009 NOV 23 ... colleagues. The researchers concluded: "Moreover, SFRP5 inhibits cervical tumorigenesis through interfering Wnt pathway in vitro." Lin and colleagues published ...
2009 NOV 23 ... fibers found in the abdominal cavity suggests that asbestos stimuli are related to the tumorigenesis of malignant peritoneal mesothelioma." Kurimoto and colleagues published ...
2009 NOV 23 ... genomic instability of both epithelial and stromal cells is important for colorectal tumorigenesis, as well as remodeling and morphological alterations of mucosal crypts. To clarify roles ...
2009 NOV 23 ... play an important role in cancer bone metastasis. To investigate the effects of CCL2 on tumorigenesis and its potential effects on bone metastasis of human prostate cancer, CCL2 was ...
2009 NOV 23 ... in the reversible regulation of protooncogene transcription, cell proliferation, and tumorigenesis in mice. The experiments involved increasing expression of PSF or VL30-1 RNA in NIH/3T3 ...
2009 NOV 27 ... (PKA)-mediated phosphorylation of Rap1b is required for cAMP-dependent mitogenesis, tumorigenesis, and inhibition of AKT activity. However, the role of phosphorylation still remains ...
2009 NOV 23 ... implies that most genetic changes precede phenotypic 'progression,' early in tumorigenesis," wrote A.E. Horvai and colleagues, University of California, Department of Pathology. ...
2009 NOV 24 ... signaling caused by inactivation of tumor suppressors results in abnormal development or tumorigenesis. We further revealed that overexpression of menin reduces beta-catenin nuclear ...
2009 NOV 23 ... India, "Etiology of cervical cancer is associated with excessive inflammation mediated tumorigenesis. Pro and anti-inflammatory cytokines (tumor necrosis factor alpha, TNFA and interleukin, ...
