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2009 JUN 1 -- "Mutations in mitochondrial DNA are associated potentially with nonsyndromic and aminoglycoside-induced hearing loss. Several nucleotide changes associated with hearing impairment were described; however, a variable frequency of......
2009 MAY 4 -- Current study results from the report, 'Neuropeptide urocortin 1 and its receptors are expressed in the human liver,' have been published. According to a study from Greece, "The corticotropin-releasing hormone (CRH) system, consisting of......
2009 NOV 16 -- According to recent research from Naples, Italy, "Urocortin (UCN) is a 40 aminoacid peptide which belongs to corticotropin-releasing factor (CRF) family. This family of peptides stimulates the secretion of proopiomelanocortin (POMC)-derived......
2009 SEP 28 -- "The aim of this study is to evaluate the positive inotropic effect of urocortin (Ucn) and to characterize its signalling pathways. Contractility was measured in ex vivo Langendorff-perfused hearts isolated from Wistar rats," scientists writing......
2009 JUN 30 -- "We have determined the complete mitochondrial genome of the yellow-spotted long horned beetle, Psacothea hilaris (Coleoptera: Cerambycidae), an endangered insect species in Korea. The 15,856-bp long P. hilaris mitogenome harbors gene content......
2009 APR 13 -- According to recent research from the United States, "Corticotropin-releasing hormone (CRH) is a key regulator of the mammalian stress response, mediating a wide variety of stress-associated behaviors including stress-induced inhibition of......
2009 MAY 25 -- "Maternal defense (also known as maternal aggression) is impaired by corticotropin-releasing factor(CRF) related peptides. but where these peptides inhibit defense is unknown. Lateral septum (LS) gates reactivity to stressors, contains......
2009 JAN 5 -- According to a study from Antwerp, Belgium, "Specific mitochondrial DNA (mtDNA) mutations in 12SrRNA and tRNASer(UCN) cause non-syndromic hearing loss (NSHL). In this study, we screened 466 hearing loss (HQ patients, negative for GJB2......
2009 JUL 27 ... silencing by independent siRNAs as well as CHK1 pharmacologic inhibition by Go6976 and UCN-01. In parallel, an siRNA screen designed to identify gene silencings synthetically lethal ...
2009 APR 20 ... Pfeiffer, and Toledo DLBCL cell lines were subsequently treated with rapamycin and UCN-01 alone or in combination. Cell proliferation, apoptosis, and cell cycle progression were ...
2009 FEB 9 ... a key regulator of cell cycle progression and DNA repair, and inhibitors of Chk1 (e.g., UCN-01 and EXEL-9844) potentiate the cytotoxic actions of chemotherapeutic drugs in tumor ...
