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2009 NOV 16 ... Emergency Investigational New Drug (E-IND) protocols against adenovirus and progressive vaccinia in immune-compromised patients. Dr. Painter said, with regard to both the ... for Chimerix, spoke at the WHO 11th meeting of the Advisory Committee on Variola Virus Research in Geneva, Switzerland, on Wednesday, November 4, 2009. George Painter, Ph.D., ...
2009 NOV 16 ... highly dependent on the assay system. The most robust activities were obtained with a vaccinia virus-based expression and reporter gene activation assay for cell fusion. In an alternative ...
2009 NOV 17 ... was measured in live BALB/c mice following lethal challenge with a recombinant WR vaccinia virus expressing luciferase. Intravenous vaccinia immunoglobulin treatments were used to ...
2009 OCT 19 ... T-cell response in LP and IEL compartments after intrarectal immunization with modified vaccinia virus Ankara (MVA). CD8(+) T cells in the IEL compartment had much lower avidity than in the ...
2009 NOV 16 ... According to a study from the United States, "Cellular tropism of vaccinia virus (VACV) is regulated by host range genes, including K1L, C7L, and E3L. While E3L is known ...
2009 NOV 16 ... MDA5. Furthermore, RNA from cells infected with encephalomyocarditis virus or with vaccinia virus and precipitated with the anti-dsRNA antibody can bind to MDA5 and induce MDA5-dependent ...
2009 OCT 19 ... particles," investigators in the United States report. "In the case of vaccinia virus, trimers of 63-kDa D13 polypeptides form the building blocks of the lattice. In the ...
2009 NOV 2 ... skin infection that develops in individuals with atopic dermatitis after exposure to the vaccinia virus (VV). Despite advances in modern medicine, there are few options for those suffering ...
2009 OCT 20 ... orthopoxviruses like variola virus, monkeypox virus, and cowpox virus (CPXV), but not vaccinia virus, encode a unique family of ankyrin (ANK) repeat-containing proteins that interact ...
2009 NOV 2 ... the B5 protein, an important neutralizing target of the extracellular envelope form of vaccinia virus (EV)," scientists in the United States report. "LC16m8 elicited a ...
2009 NOV 24 ... confirmed by amplicon sequencing. Exanthematic lesion samples collected during bovine vaccinia or contagious ecthyma outbreaks were submitted to OPV/PPV nested-multiplex PCR and ... Federal University of Minas Gerais, Dept. of Microbiology, Institute Ciencias Biology, Virus Laboratory, Av Antonio Carlos, 6627 Caixa Postal 486, BR-31270901 Belo Horizonte, MG, ...
2009 NOV 2 ... may facilitate virus replication and sequence evolution. In a phase 1 trial of modified vaccinia virus Ankara/fowlpox virus-based HIV-1 vaccines in 20 HIV-infected young adults receiving ...
2009 NOV 2 ... Scientists discuss in 'Lister strain of vaccinia virus armed with endostatin-angiostatin fusion gene as a novel therapeutic agent for human ...
2009 NOV 10 ... According to a study from Belo Horizonte, Brazil, "Vaccinia virus (VACV) has been associated with several bovine vaccinia outbreaks in Brazil, causing ...
2009 NOV 16 ... in the cytoplasm of the host cell. In this context, we investigated the function of the vaccinia virus G5 protein because it belongs to the FEN1-like family of nucleases and is conserved in ...
2009 OCT 19 ... prime-boost is a common vaccination strategy to elicit CD8(+) T cells (TCD8+), and vaccinia virus (VACV) has been widely used as a boosting vector," researchers in Canberra, Australia ...
2009 NOV 2 ... vaccination occurring in patients with atopic dermatitis. In affected individuals, vaccinia virus (VV) spreads through the skin, resulting in large primary lesions and satellite lesions, ...
