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2009 NOV 23 ... in Nature, Drs. Bradner and Verdine showed in multiple models, including T-cell acute lymphoblastic leukemia (T-ALL), that Stapled Peptides achieved tight direct binding to the Notch transcription ...
2009 NOV 16 ... heavily pretreated patients with resistant and refractory CML and Philadelphia-positive acute lymphoblastic leukemia, including those with the T315I mutant variant of the target protein, BCR-ABL. ...
2009 NOV 9 ... "The large MRC/ECOG Adult Acute Lymphoblastic Leukemia Study establishes the value of sibling donor allogeneic transplantation in patients with ...
2009 NOV 16 ... with imatinib-resistant and -intolerant CML and Philadelphia chromosome-positive acute lymphoblastic leukemia. Nilotinib, an analog of imatinib, more potent than its parent compound, is another ...
2009 NOV 2 ... Scientists discuss in 'MEK inhibitors potentiate dexamethasone lethality in acute lymphoblastic leukemia cells through the pro-apoptotic molecule BIM' new findings in...
2009 NOV 16 ... 5 months after allogeneic bone marrow transplantation from an unrelated donor for acute lymphoblastic leukemia," scientists in Chiba, Japan report. "His renal biopsy showed membranous ...
2009 NOV 27 ... damaged, or mutated, in patients with a form of blood cancer, known as T-ALL or T-cell acute lymphoblastic leukemia.Abnormal NOTCH genes found in cancer patients remain in a state of constant ...
2009 NOV 23 ... determinations for assessing compliance with maintenance therapy for childhood acute lymphoblastic leukemia,' is now available. According to recent research published in the journal Leukemia & ...
2009 NOV 2 ... stem cell transplantation is a potential therapeutic approach for adults with high-risk acute lymphoblastic leukemia in remission: results of a prospective phase 2 study,' are detailed in a study ...
2009 NOV 16 ... According to a study from Iran, "Acute lymphoblastic leukemia (ALL) presenting with musculoskeletal pain may be difficult to distinguish from juvenile ...
2009 NOV 9 ... their offering. The drug therapy of acute myeloid leukemia (AML) and adult acute lymphoblastic leukemia (ALL) is largely based on chemotherapy regimens that have changed little in the past few ...
2009 NOV 16 ... to 80 percent overall. When St. Jude opened its doors in 1962, the survival rate for acute lymphoblastic leukemia (ALL), the most common form of childhood cancer, was 4 percent. Today, the survival rate ...
2009 NOV 9 ... W Harrison St., Chicago, IL 60612, USA. Keywords: United States, Durham, Acute Lymphoblastic Leukemia, Bone Marrow, Clinical Pathology, Cytometry, Hematology, Oncology, Residual Neoplasm, ...
2009 NOV 9 ... to recent research published in the journal Clinical Lymphoma & Myeloma, "T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) are considered the same disease, ...
2009 NOV 9 ... bone marrow microenvironment provides critical support for the growth and survival of acute lymphoblastic leukemia cells and protection against the effects of chemotherapeutic agents. Although the ...
2009 NOV 2 ... Kingdom, "We report 2 novel, cryptic chromosomal abnormalities in precursor B-cell acute lymphoblastic leukemia (BCP-ALL): a translocation, either t(X;14)(p22;q32) or t(Y;14)(p11;q32), in 33 patients ...
2009 NOV 2 ... Investigators publish new data in the report 'Interphase FISH on TEL/AML1 positive acute lymphoblastic leukemia relapses--analysis of clinical relevance of additional TEL and AML1 copy number ...