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2009 NOV 29 -- Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have eliminated cervical cancer in mice with two FDA-approved drugs currently used to treat breast cancer and osteoporosis. Published in this......
2009 NOV 28 -- GTC Biotherapeutics, Inc.'s ("GTC", NASDAQ: GTCB) total net loss for the third quarter ended September 27, 2009 was $5.1 million, or $0.48 per share, compared with $6.1 million, or $0.59 per share, in the third quarter of 2008. The total net......
2009 NOV 28 -- Shire plc , the global specialty biopharmaceutical company, announced the availability of INTUNIV™ (guanfacine) Extended Release Tablets in pharmacies across the United States for the treatment of Attention-Deficit/Hyperactivity Disorder......
2009 NOV 27 -- According to recent research from the United States, "Bone morphogenetic proteins (BMPs) require proteolytic activation by members of the proprotein convertase (PC) family. Pro-BMP4 is initially cleaved at a site adjacent to the mature ligand......
2009 NOV 27 -- "The X-ray emission properties of nitrogen plasmas are numerically investigated using corona plasma equilibrium model. The X-ray emission intensities of nitrogen Ly (alpha) , Ly (beta) and He (alpha) , He (beta) lines are calculated,"......
2009 NOV 27 -- "Density functional theory electronic structure calculations are used to compute equilibrium constants for iron-isotope exchange among Fe2+(aq), Fe3+(aq), and hematite (alpha-Fe2O3). The hematite is represented in both bulk and surface......
2009 NOV 27 -- According to a study from Beijing, People's Republic of China, "The circular dichroism (CD) spectra of (1,8,15,22-tetraalkoxylphthalocyaninato)lead complexes Pb[Pc(alpha-OCH3)(4)] (1), Pb[Pc(alpha-OC2H5)(4)] (2), and Pb[Pc(alpha-OC5H11)(4)] (3)......
2009 NOV 27 -- "The pathway of D-xylose degradation in archaea is unknown. In a previous study we identified in Haloarcula marismortui the first enzyme of xylose degradation, an inducible xylose dehydrogenase (Johnsen, U., and Schonheit, P. (2004) J.......
2009 NOV 27 -- According to recent research from South Korea, "DAX-1 (dosage-sensitive sex reversal adrenal hypoplasia congenital critical region on X chromosome, gene 1) is an atypical member of the nuclear receptor family and acts as a corepressor of a......
2009 NOV 27 -- "The 1-phenylselenocyclopropylmethyl cations are generated by the reaction of the corresponding cyclopropylmethanols 1 with TsOH," investigators in Kanazawa, Japan report. "The reaction in methanol proceeds to afford the homoallylic......
2009 NOV 27 -- "Maspin is a serpin that has multiple effects on cell behavior, including inhibition of migration. How maspin mediates these diverse effects remains unclear, as it is devoid of protease inhibitory activity," scientists writing in the Journal of......
2009 NOV 27 -- "The neurosteroid allopregnanolone (AP) is a GABAergic agonist that suppresses central nervous system (CNS) activity in the adult brain, and by reducing excitotoxicity is considered to be neuroprotective. A role for neurosteroids in the......
2009 NOV 27 -- "An assessment of the relative reactivities of the 4-OH of N-acetylglucosamine acceptors bearing simple protecting groups, beta-linked or alpha-linked D or L sugars at O-3 is presented, using a per-O-acetylated alpha-D-glucosyl......
2009 NOV 27 -- "Mono-n-butyltin(IV) dichloride complex with the general formula [n-BuSnCl2(PAP)] has been synthesized by direct reaction of n-BuSnCl3 with pyruvic acid-2-pyridylhydrazone in the presence of KOH in equimolar ratio in absolute methanol under......
2009 NOV 27 -- "In January 2006 the beryllium reflector and graphite wedge that contained the k(0) INAA irradiation position were replaced at the University of Missouri Research Reactor," scientists writing in the Journal of Radioanalytical and Nuclear......
2009 NOV 27 -- "The present study tests the hypothesis that the structure of extracellular domain Loop 2 can markedly affect ethanol sensitivity in glycine receptors (GlyRs) and gamma-aminobutyric acid type A receptors (GABA(A)Rs). To test this, we mutated......
2009 NOV 27 -- According to recent research from Regina, Canada, "The Rh-2(MPPIM)(4)-catalyzed intraniolecular C-H insertion reaction of (S)- and ®-1-benzyl-5-(alpha-diazoacetoxy)piperidin-2-one and (S)-1-benzyl-4-(alpha-diazoacetoxy)pyrrolidin-2-one......
2009 NOV 27 -- According to recent research from Hangzhou, People's Republic of China, "The homolytic bond dissociation enthalpies (BDEs) of the acidic C-H bonds in it series of phosphonates and related phosphorus-containing Compounds have been determined by......
2009 NOV 27 -- "Key transmembrane proteins in the innate immune system, Toll-like receptors (TLRs), have been suggested to occur in the genome of non-mammalian organisms including invertebrates. However, authentic invertebrate TLRs have been neither......
2009 NOV 27 -- "Microwave irradiation promotes the rapid and efficient reaction of I thiophenol and aryl or heteroaryl halide using it copper or palladium catalyst and it range of ligands, depending upon substrate," scientists in Wales report. "Of......
