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2009 NOV 27 -- "Produced water from offshore oil production platforms represents the largest direct discharge of effluent into the offshore environment Produced water effluents contain a complex mixture of substances which are known to bind to the estrogen......
2009 NOV 23 -- GTx, Inc. (Nasdaq: GTXI) reported financial results for the third quarter of 2009. The net loss for the third quarter and nine months ended September 30, 2009 was $12.8 million and $35.4 million, respectively, compared with a net loss of $11.9......
2009 NOV 23 -- Fresh data on prostate cancer are presented in the report 'Induction of apoptosis in the LNCaP human prostate carcinoma cell line and prostate adenocarcinomas of SV40T antigen transgenic rats by the Bowman-Birk inhibitor.' "The soybean-derived......
2009 NOV 18 -- "Common male reproductive abnormalities including cryptorchidism, hypospadias, and low sperm counts may comprise a testicular dysgenesis syndrome (TDS), resulting from fetal testis dysfunction during a critical developmental period involving......
2009 NOV 23 -- According to a study from the United States, "Androgen deprivation therapy for prostate cancer is associated with osteoporosis and increased fracture risk. Previous studies of zoledronic acid demonstrated bone loss prevention in patients......
2009 NOV 23 -- "Oesophageal adenocarcinoma (OAC) is more common in men. Androgens may therefore contribute to the pathogenesis of OAC," scientists writing in the journal Cancer Causes & Control report. "Prostate cancer (PC), an androgen......
2009 NOV 26 -- According to recent research from South Korea, "Piceatannol (trans-3,4,30,50-tetrahydroxystilbene) is a polyphenol that is found in grapes, red wine, Rheum undulatum, and the seeds of Euphorbia lagascae. It has been previously reported that......
2009 NOV 23 -- Current study results from the report, 'HE3235 inhibits growth of castration-resistant prostate cancer,' have been published. According to recent research from the United States, "Treatments for advanced prostate cancer (CaP) typically involve......
2009 NOV 23 -- According to recent research from Shanghai, People's Republic of China, "We developed an organotypic genital tubercle culture system in vitro and used it to investigate the direct effects of the hyperestrogenic state on fetal mouse penile and......
2009 NOV 23 -- According to recent research from the United States, "High consumption of cruciferous vegetables is associated with a reduced risk of prostate cancer in epidemiological studies. There is preliminary evidence that sulforaphane, derived from......
2009 NOV 23 -- According to a study from Mexico, "Dehydroepiandrosterone (DHEA) has a protective role against epithelial-derived carcinomas; however, the mechanisms remain unknown. We determined the effect of DHEA on cell proliferation, the cell cycle and cell......
2009 NOV 24 -- "The modulating effect of IGF-I on the regulation of AR gene expression and activation in skeletal muscle cells remains poorly understood. In this study, the effects of IGF-I treatment on AR induction and activation in the absence of AR ligands......
2009 NOV 23 -- According to a study from Hamilton, Canada, "A 49-year-old patient with high-risk prostate cancer presented to a specialist. He was treated with neoadjuvant hormonal therapy for 6 months, followed by conformal radiotherapy." ......
2009 NOV 23 -- "Fat mass is increased in hypogonadal men and the changes are reversed by testosterone replacement. Testosterone administration enhances whole body fat oxidation (Fox)," researchers in Australia report. "Fat is oxidized in the......
2009 NOV 23 -- According to recent research from the United States, "The profound hypogonadism due to androgen deprivation therapy for prostate cancer results in complications such as sexual dysfunction, poor quality of life, vasomotor symptoms and altered......
2009 NOV 23 -- Investigators publish new data in the report 'Prostate cancer survivorship: prevention and treatment of the adverse effects of androgen deprivation therapy.' According to recent research published in the Journal of General Internal Medicine,......
2009 NOV 24 -- "This study tested the hypothesis that the estrogen receptor (ESR) pathway, androgen receptor (AR) pathway, or both mediate estrogen-induced developmental penile disorders. Rat pups received diethylstilbestrol (DES), with or without the ESR......
2009 NOV 23 -- Tokai Pharmaceuticals, Inc., a biopharmaceutical company focused on developing new treatments for prostate cancer, announced the initiation of a Phase 1/2 clinical trial of its lead candidate TOK-001 for the treatment of patients with castration......