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2009 NOV 23 ... several "subunits" of the NMDA receptor. This receptor, formally called the N-methyl-D-aspartate receptor, belongs to a family of cellular receptors that mediate excitatory nerve ...
2009 NOV 23 ... attached through a phosphoramidate linkage to the alpha-carboxyl group of the terminal aspartate." "McC is a Trojan horse inhibitor: it is actively taken inside sensitive ...
2009 NOV 23 ... in both groups (50%). H-1-MR spectroscopy revealed a significant decrease of N-acetyl aspartate only in vermis in the MIDD group, suggesting functional defect and/or neuronal loss. ...
2009 NOV 17 ... the United States, "Clinical and experimental data suggest dysregulation of N-methyl-D-aspartate receptor (NMDAR)-mediated glutamatergic pathways in schizophrenia. The interaction ...
Subject: Pharmacology and Experimental Therapeutics
2009 NOV 24 ... published in the journal Neuroscience, "Activity-dependent modulation of N-methyl-D-aspartate (NMDA) receptors containing selective NR2 subunits has been implicated in plastic ...
2009 NOV 23 ... for the biosynthesis of the neurotransmitter D-Scrine, which activates N-methyl-D-aspartate (NMDA) receptors in the CNS. Aberrant regulation of NMDA receptor signaling has been ...
2009 NOV 23 ... EphB2 receptor, has tyrosine kinase activity, and directly phosphorylates the N-methyl-D-aspartate receptor (NMDAR) subunits in both cell lines and primary neuronal cultures. This ...
2009 NOV 23 ... processes, however the cellular sites of interaction between agonists of N-methyl-D-aspartate (NMDA) and p-opioid receptors (mu OR) in the CeA are unknown," investigators in the ...
2009 NOV 23 ... reductase, a promiscuous NADPH-dependent enzyme that is a paralogue of aspartate semialdehyde dehydrogenase. Succinic semialdehyde is then reduced with NADPH to ...
2009 NOV 20 ... 0.01), perisinusoidal fibrosis (P < 0.001), and NAS >= 5 (P < 0.005). Serum aspartate aminotransferase levels were the only clinical or laboratory data that independently ...
2009 NOV 23 ... respectively) relative to SED (6.72 +/- 0.57 nmol h x 10(5) cell(-1), P< 0.05). Aspartate increased in EXT (9.72 +/- 1.14 nmol h x 10(5) cell(-1)) as compared to SED (1.10 +/- ...
2009 NOV 23 ... EXACERBATES THE ETHANOL WITHDRAWAL SYNDROME IN RODENTS AND ACTIVATES N-METHYL-D-ASPARTATE GLUTAMATE RECEPTORS TO PRODUCE PERSISTING SP. Neuroscience, 2009;163(3):868-876). ...
2009 NOV 16 ... receptor interaction in the amygdala with GABARAP inhibitory peptide blocked N-methyl-D-aspartate-mediated GABA(A) receptor insertion in the amygdala. Importantly, it also blocked ...
2009 NOV 26 ... (GSH), catalase (CAT), superoxide dismutase (SOD), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and vitamins E and C. indicated a significant reduction in the ...
2009 NOV 16 ... with CK-18 fragments or NASH on univariate analysis (fibrosis, alanine aminotransferase, aspartate aminotransferase, age, biopsy length). The area under the receiver operating ...
2009 NOV 25 ... flexibility.'' Lesion, temporary inactivation, and infusion of an N-methyl-D-aspartate (NMDA)-receptor antagonist into the dorsomedial striatum (dmSTR) impair reversal ...