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2009 NOV 23 ... potential of this subset of pancreas-committed hUCB-derived MNCs will provide us with an autologous source of 'lineage-committed' progenitors for cell replacement therapy in diabetes." ... 2009;78(4):232-40). For additional information, contact V.S. Parekh, Stem Cells and Diabetes Section, Laboratory #12, National Center for Cell Science, ... ability to differentiate into insulin-producing cells. We observe that after 9 weeks of transplantation, approximately 25% grafts exhibit human insulin-producing (16% immunopositive) cells. ...
2009 NOV 9 ... acute myeloid leukemia or myelodysplasia patients were immunized with irradiated, autologous, GM-CSF-secreting tumor cells early after allogeneic, nonmyeloablative HSCT. Despite the ... "Through an immune-mediated graft-versus-leukemia effect, allogeneic hematopoietic stemcelltransplantation (HSCT) affords durable clinical benefits for many patients with ...
2009 NOV 16 ... control of acute emesis in patients receiving multiday-high dose chemotherapy before autologous stem cell transplantation. The addition of a second dose of palonosetron after 48 hours significantly reduces the ...
2009 NOV 2 ... presentation of their safety and feasibility study demonstrating the administration of autologous bone marrow derived stem cells for the treatment of acute and chronic spinal cord injury ... will feature data published earlier this year by DaVinci Biosciences in issue 17 (12) of CellTransplantation, a peer-reviewed scientific journal focused on regenerative medicine. ...
2009 NOV 2 ... review the current status of stem cell mobilization for myeloma as well as the role of autologous stem cell transplantation in this disease. On June 1, 2008, a panel of experts was convened by the International ...
2009 NOV 9 ... heart disease, and liver disease. This reprogramming technique may allow 'autologouscelltransplantation', where the donor of the cells is also the recipient. This is ... Scientists have overcome a key barrier to the clinical use of stem cells with a technique which transforms regular body cells into artificial stem cells ...
2009 NOV 2 ... first-line therapy of WM and should take into account specific treatment goals, future autologous stem cell transplantation eligibility, and long-term risks of secondary malignancies. In the salvage setting, the ...
2009 NOV 23 ... 120 patients enrolled in a Phase III trial of maintenance therapy +/-thalidomide after autologous stem cell transplantation. TCR Vbeta repertoire analysis identified T cell expansions in 48% of patients ...
2009 NOV 2 ... antibody augmented NK cell-mediated lysis of HLA-C-expressing tumor cells, including autologous AML blasts, but did not induce killing of normal peripheral blood mononuclear cells, ... and increased survival in acute myeloid leukemia (AML) patients upon haploidentical stem cell transplantation from KIR-mismatched donors." "To exploit this ...
2009 NOV 2 ... iron in haematological patients during chemotherapy and conditioning for autologous stem cell transplantation,' is the subject of a report. According to recent research from Helsinki, Finland, ...
2009 NOV 16 ... doxorubicin, and dexamethasone) and subsequent high-dose melphalan, followed by autologous peripheral blood stemcelltransplantation. Because this patient did not have any ...
2009 NOV 16 ... differentiation and progenitor cell markers in corneal tissues that previously underwent autologous cultivated oral mucosal epithelial transplantation (COMET). Four eyes from three ... small, compact cells in the basal epithelium preferentially expressed the keratinocyte stem/progenitor cell markers, which may be indicative of the engraftment of the progenitor ...
2009 NOV 28 ... that occurs immediately before or at the timing of neutrophil engraftment following autologous or allogeneic SCT. It is characterized by fever, skin rash, and non-cardiac pulmonary ... in Pediatric Transplantation (Engraftment syndrome following allogeneic hematopoietic stemcelltransplantation in children. Pediatric Transplantation, ...
2009 NOV 9 ... be beneficial. Strategies for stemcelltransplantation (SCT) in T-LBL and T-ALL differ. Autologous SCT in complete remission (CR) in T-LBL gives a 70% survival rate, which is similar to ...
2009 NOV 23 ... complete response (CR) could be shown only after introduction of high-dose therapy plus autologous stem cell transplantation (ASCT). In the context of ASCT, achieving CR (negative immunofixation and normal bone ...
2009 NOV 16 ... (0.5, 5 mg) in healthy volunteers, and open-label, single intravenous 5 mg doses in autologous HSCT recipients. Single and multiple doses of hLF1-11 were tolerable up to 5 mg ... "The treatment of patients with haematological malignancies by means of haematopoietic stemcelltransplantation (HSCT) is often accompanied by life threatening infections. With ...
2009 NOV 27 ... proliferation and differentiation of endogenous cells at the damaged site and the autologoustransplantation Recent findings Self-repair refers to a favorable structural and ... immune rejection is to introduce autologous cells. Ependymal cells, induced pluripotent stem cells, and olfactory neuroepithelial cells have been recognized as promising sources, ... recognized as promising sources, which will spur ongoing efforts to evaluate these new cell sources for cell replacement therapy," wrote D.G. Wei and colleagues, University of ...
2009 NOV 9 ... of plerixafor (AMD3100), a CXCR4 antagonist, in mobilizing hematopoietic stem cells for autologousstem-celltransplantation in non-Hodgkin's lymphoma (NHL) patients. This is a phase ...
