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2009 NOV 16 ... recognize leucocyte antigens in the transfused host or the infusion of lipids and other biological response modifiers that accumulate during the storage or processing of blood components. TRALI appears to ...
2009 OCT 19 ... mechanisms, key participants in the cerebral response to ischemia. On the basis of these biological activities, they were selected as candidate genes for further investigation. We analyzed ... that polymorphisms in genes encoding proteins involved in these reactions could act as modifiers of the cerebral response to ischemia and impact the resultant stroke volume," ...
2009 MAR 30 ... sell and distribute SF-1019, a compound that was developed from extensive research into Biological Response Modifiers (BRMs). Argyll Biotechnologies, LLC has initiated efforts to seek regulatory approval of ...
2009 NOV 23 ... for sequential monitoring, manipulation and kinetic analyses of the effects of drugs, biological response modifiers and gene expression in both adherent and non-adherent cells held on the chip. Here we ...
2009 AUG 17 ... Ledford and colleagues published their study in Expert Opinion on Biological Therapy (Omalizumab: overview of pharmacology and efficacy in asthma. Expert Opinion on ... beta agonists and leukotriene modifiers. Approximately 60% of treated subjects show a response and 12 - 16 weeks are generally needed to evaluate response. Omalizumab is ...
2009 OCT 19 ... and a truncated scorpion beta-toxin, has prompted us to examine and compare their biological effects." "Drosomycin is the most expressed antimicrobial peptide in ... is the most expressed antimicrobial peptide in Drosophila melanogaster immune response. A truncated scorpion beta-toxin is capable of binding and inducing conformational ... insect antimicrobial peptides, plant protease inhibitors, and ion channel gating modifiers, as well as blockers from scorpions, bear a common CS alpha beta scaffold. The high ...
2009 MAR 23 ... function."
Shao and colleagues published their study in the Journal of Biological Chemistry (Sumoylation Regulates the Transcriptional Activity of MafA in Pancreatic beta ... the ins gene promoter, which plays a critical role in regulating ins gene expression in response to glucose," scientists in the United States report.
"Here, we show ... we show that MafA is post-translationally modified by the small ubiquitin-related modifiers SUMO-1 and -2. Mutation of a single site in MafA, Lys(32), blocks its sumoylation in ...
2009 JUL 20 ... arthritis therapies, with a focus on the specific class of drugs, known as the biological response modifiers (BRMs). Biological response modifiers have ...
2008 AUG 25 ... of the immune system have led to encouraging results. These new treatments ¡V primarily biological response modifiers ¡V have significant side effects and require close patient monitoring. But their ability ...
2008 NOV 24 ... particularly involved in new strategies in the treatment of allergic disease, including biological response modifiers, such as specific immunotherapy.
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2008 AUG 25 ... These studies show that scientists need to identify confounders and modifiers of the biologicalresponse to vitamin D, including dietary factors, lifestyle factors such as exercise, ...
2008 NOV 10 ... St., New York, NY 10013, USA.
Keywords: Japan, Tokyo, Anticancer Therapy, Biological Response Modifiers, Biological Therapy, Cancer, Immunology, Immunotherapy, Oncology, Treatment.
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2008 DEC 1 ... Data detailed in 'Targeted therapies and biologicalmodifiers in urologic tumors: pathobiology and clinical implications' have been ... cells in the body limit the dosage to a level below that which is effective for complete response. There has been a search for more specific agents that have a much greater effect on ...
2008 JUN 23 ... "Therefore, our evidences are to be taken in consideration when both the effects of biologicalmodifiers are tested and OCs apoptosis molecular mechanisms are investigated."
... of therapeutic manipulation, the OCs are extensively employed to investigate cell response to therapies for the treatment of bone loss associated with several diseases, including ...
2008 AUG 25 ... SF-1019 is a compound that was developed from extensive research into Biological Response Modifiers. This research suggests that SF-1019 has the potential to affect a number of clinical ...
2008 OCT 6 ... development of interventions intended to change cancer-related health status (drugs or biological agents, immune responsemodifiers, interventive devices, and life-style alterations). ...
