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2009 NOV 24 ... tomography (PET) tracer to assess the distribution of P-glycoprotein (P-gp) at the blood-brain barrier (BBB) in vivo, the potent third-generation P-gp inhibitor elacridar (1) was labeled with ...
2009 NOV 23 ... However, the TNFR ECD is a large molecule therapeutic that does not cross the blood-brain barrier (BBB)," researchers in the United States report. "Human TNFR ECD was ...
2009 NOV 23 ... exposure of the female immune system to paternal antigens following intercourse (without barrier contraception) [could induce] tolerance of the maternal immune system to the paternal ...
2009 NOV 26 ... to the functional preservation of the intestinal epithelium as a first line of mucosal barrier against infectious agents through retaining the number of certain IELs," wrote O. ...
2009 NOV 23 ... in response to mild hypoglycemia. VEGF is implicated in glucose transport over the blood-brain barrier, and the increase during hypoglycemia has been positively correlated with preservation ...
2009 NOV 16 ... is a tertiary amine, which may act both in the periphery and/or pass through the blood-brain barrier (BBB) in unionized form and exhibit a central effect," scientists in Iran report. ...
2009 NOV 16 ... Few therapeutic strategies exist for the treatment of brain metastases because the blood-brain barrier severely limits drug access," investigators in the United States report. ...
2009 NOV 16 ... Immune cell migration to the CNS was assessed in vitro with primary cultures of human blood-brain barrier (BBB)-derived endothelial cells, and in vivo in EAE mice. We demonstrate that in ...
2009 NOV 28 ... to explain the molecular reasons for its success, especially the ability to cross the blood-brain barrier.Keywords: Biochemical, Chemicals, Chemistry, Pediatrics, Biochemical, Cancer ...
Subject: Cincinnati Children's Hospital Medical Center
2009 NOV 16 ... and lack of confidence (14 percent). More than one in ten people cited stress as the barrier preventing them from making lifestyle and behavior changes (14 percent of adults ...
2009 NOV 16 ... by RNA interference in Sertoli cells cultured in vitro with established TJ permeability barrier that mimicked the blood-testis barrier (BTB) in vivo. Mislocalization of N-cadherin and ...
2009 NOV 23 ... negatively charged liposomes were injected into the tail vein of rats, and blood/brain barrier (BBB) targeting was determined by confocal microscopy as a function of the temporal ...
2009 NOV 23 ... of Toxicology. The researchers concluded: "The ability of MA to cross the blood-brain barrier (log p=-0.32; polar surface area 3.88) provides prerequisites for a potential use of the ...
2009 NOV 23 ... The researchers concluded: "However, INSL3 evidently traverses the blood-testis barrier to enter the seminiferous compartment, rete testis, and epididymis in sufficient ...
2009 NOV 16 ... endothelium of the diabetic retina, which results in endothelial injury, blood-retina barrier breakdown, and capillary nonperfusion. Leukocyte adhesion is triggered by the ...
2009 NOV 16 ... and lack of confidence (14 percent). More than one in ten people cited stress as the barrier preventing them from making lifestyle and behavior changes (14 percent of adults ...
