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2009 SEP 28 ... that it can be used as a model system for investigating and predicting drug induced cardiotoxicity, officials from the firms announced. Stemina is a Madison, Wisconsin-based ...
2009 SEP 28 ... industry consortium to validate a human cell model and analysis system for preclinical cardiotoxicity testing of pharmaceutical candidate compounds. The consortium will be formally launched ...
2009 AUG 18 ... said Dr. Jotte. "Additionally, these data suggest that Amrubicin has an improved cardiotoxicity profile compared to traditional anthracyclines. We believe these results warrant further ...
2009 SEP 21 ... deviations from the planned chemotherapy schedule. There were no severe adverse events, cardiotoxicity or neutropenia. with negative estrogen or progesterone receptors, or high KI-67 suffered ...
2009 OCT 12 ... of the drug even after disease progression in combination with chemotherapy. While cardiotoxicity Is well recognized with trastuzumab, unusual pulmonary toxicities are becoming ...
2009 SEP 14 ... British Columbia. The researchers concluded: "Troglitazone has potential cardiotoxicity at high doses but, at lower concentrations, does not prevent cardiac lipotoxicity, which ...
2009 SEP 7 ... new data in the report 'Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death.' "Dexrazoxane ...
2009 SEP 7 ... exposed workers. Unprotected occupational exposure to chlorofluorocarbons can induce cardiotoxicity in the form of cardiac arrhythmias," wrote L.M.E. Sabik and colleagues, Zagazig ...
2009 NOV 2 ... This prospective open labeled, multicenter phase II study assessed the potential cardiotoxicity and efficacy of PLD and trastuzumab as first and second line combination therapy in ...
2009 NOV 23 ... the United Kingdom, "CB1 antagonism is associated with reduced doxorubicin-induced cardiotoxicity and decreased cerebrocortical infarction. Rimonabant, a selective CB1 receptor ...
2009 NOV 9 ... Fragasso and colleagues published their study in Heart and Vessels (Cardiotoxicity after low-dose chloroquine antimalarial therapy. Heart and Vessels, 2009;24(5):385-387). ...
2009 NOV 16 ... pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity. Biochemical Journal, 2009;422(Part 3):513-520). For additional ...
2009 SEP 28 ... to a study from Winnipeg, Canada, "The incidence and management of trastuzumab-mediated cardiotoxicity outside of clinical trials has not been well described. The aim of the study was to ...
2009 SEP 7 ... the preventive role of S-allyl cysteine sulphoxide (SACS) in isoproterenol (ISO)-induced cardiotoxicity in male Wistar rats. Myocardial infarction was induced by subcutaneous injection of ISO ...
2009 NOV 23 ... used effectively in the treatment of several childhood malignancies. During treatment, cardiotoxicity caused by cell damage due to the free oxygen radicals that are generated is a major ...
2009 NOV 9 ... expression of sarcomeric proteins, and increased tissue damage associated with Dox cardiotoxicity. Overexpression of CaMKII delta B in primary cardiac cells inhibits Dox-mediated ...
2009 SEP 7 ... preliminary evaluation of in vivo toxicology revealed a significant dose related cardiotoxicity. Here we describe the improvement of pharmacological properties of thyroid hormone ...
2009 OCT 5 ... measurements of in vivo target inhibition to demonstrate an off-target contribution to cardiotoxicity," wrote S.K. Engle and colleagues. The researchers concluded: "Additional ...
2009 SEP 14 ... nor effective." "Chronic use of CsCl has resulted in cases with severe cardiotoxicity. report. A 65-year-old lady presented to our hospital's accident and emergency ...
