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2009 NOV 24 ... receptor (GPCR) agonists. Interactions between the CXCR4 GPCR and the CXCL12 chemokine have been shown to mediate gene transcription and cellular proliferation in ...
2009 NOV 23 ... a myriad of inflammatory cells and their mediators. Thymus and activation-regulated chemokine (TARC) plays a significant role in the inflammatory phase by recruiting CCR4(+) T(H)2 ...
2009 NOV 23 ... According to a study from Munich, Germany, "Aims/hypothesis Chemokine (C-X-C motif) ligand 12 (CXCL12) (also known as stromal cell-derived factor-1 ...
2009 NOV 23 ... progression. In rodents, the nigro-striatal system exhibits high expression of the chemokine receptor CXCR4. Its natural ligand CXCL12 can promote neuronal apoptosis. Therefore, the ...
2009 NOV 23 ... into tissues, a key feature of inflammation. Through its unique receptor CX3CR1, the chemokine CX3CL1 participates in diverse inflammatory processes including arterial atherosclerosis ...
2009 NOV 23 ... accumulation of eosinophils and monocytes in the airways associated with elevated lung chemokine levels. Surprisingly, APN-/- mice developed severe pulmonary arterial muscularization ...
2009 NOV 23 ... of G-protein signaling and Rack1) and in cytokine receptors for interleukin-8 and chemokine have also been reported," wrote Y. Chertkow and colleagues, Technion, Department of ...
2009 NOV 23 ... of China, "Cx3cl1, also called fractalkine, is located at 19p12, and encodes the chemokine (C-X3-C motif) ligand 1 protein. This protein contains 393 amino acids, and is the only ...
2009 NOV 23 ... 1 diabetes. We examined islet cell status, including the presence of enterovirus and chemokine/cytokine/major histocompatibility complex (MHC) expressions in the pancreata using ...
2009 NOV 23 ... cytokine mRNA. Mesenteric lymph nodes (MLN) were assessed for forkhead boxP3 (Foxp3) and chemokine (C-C motif) receptor 7 (CCR7) expression by real-time PCR and immunostained for Foxp3(+) ...
2009 NOV 23 ... and their receptors in a standardized setting. The expression of 14 chemokines and 14 chemokine receptor genes was determined by quantitative real-time polymerase chain reaction from ...
2009 NOV 23 ... not been studied due to lack of animal models. Here, we have characterized the role of chemokine CXCL1/KC and receptor CXCR2 in adenoviral keratitis using a novel mouse model. Analysis ...
2009 NOV 23 ... New investigation results, 'Abnormalities in serum chemokine levels in euthymic patients with bipolar disorder,' are detailed in a study published ...
2009 NOV 23 ... According to recent research from the United States, "Chronic expression of CXC chemokine ligand 10 (CXCL10) in the central nervous system (CNS) following infection with the ...
2009 NOV 23 ... Investigators publish new data in the report 'The chemokine CCL2 increases prostate tumor growth and bone metastasis through macrophage and ...
2009 NOV 23 ... The researchers concluded: "Together, these results identify a novel mechanism of chemokine receptor regulation of chemotaxis and suggest that arrestins may serve as scaffolding ...
2009 NOV 24 ... study in the Journal of Allergy and Clinical Immunology (Expression of chemokines and chemokine receptors in lesional and nonlesional upper skin of patients with atopic dermatitis. ...
2009 NOV 23 ... but did not affect levels of IgG1 antimyosin antibodies. In addition, it suppressed chemokine expression and activator protein 1 activity in myoblasts in vitro. The synthetic ...
2009 NOV 23 ... and c-Kit) and the major homing signal pathway stromal cell-derived factor-1 and its chemokine receptor (CXCR4) in lung tissue from patients with idiopathic PAH, familial PAH, and PAH ...
2009 NOV 28 ... "Elevated blood levels of thymus and activation-regulated chemokine (TARC)/CCL17 have been observed in atopic dermatitis (AD) and may serve as a new ...
