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2009 NOV 16 ... different types of breast cancer. The combination of metformin and a well-defined chemotherapeutic agent, doxorubicin, kills both cancer stem cells and non-stem cancer cells in culture. ...
2009 NOV 23 ... "Convection-enhanced delivery (CED) of highly stable PEGylated liposomes encapsulating chemotherapeutic drugs has previously been effective against malignant glioma xenografts. We have ... with gadoCED showed no evidence of histopathological changes attributable to either agent," wrote A.Y. Grahn and colleagues. The researchers concluded: "The ...
2009 NOV 9 ... "Chemotherapy is one of the main treatment options for cancer, but the effectiveness of chemotherapeutic drugs is severely limited due to their systemic toxicity. Therefore, the need for a more ... more targeted approach in tumor treatment is obvious." "A tumor-activated agent would decrease systemic toxicity as well as increase the efficacy of the treatment. It ...
2009 NOV 9 ... that it has been granted its 33rd U.S. Patent, # 7,608,257, entitled "Sensitization of Chemotherapeutic Agent Resistant Neoplastic Cells With a Virus." The patent claims cover methods of using ...
2009 NOV 25 ... drugs, DNA) into target cells in vivo. Electrochemotherapy involves the injection of chemotherapeutic agent followed by a local delivery of a train of short high-voltage pulses to the tumor nodule ...
2009 NOV 16 ... lines after treatment with SD-1029. The cytotoxicity of the combination of SD-1029 and chemotherapeutic drugs is significantly better than either agent alone. Phosphorylation of Stat3 in ...
2009 NOV 9 ... growth in the small interfering UCKL-1 RNA treated K562 cell culture. In addition, the chemotherapeutic agent staurosporine was seen to be more effective in inducing cell death by apoptosis in ...
2009 NOV 23 ... "Doxorubicin (DXR) is a chemotherapeutic agent used effectively in the treatment of several childhood malignancies. During treatment, ...
2009 NOV 16 ... response to reovirus in vitro and in vivo. The combination of reovirus and several chemotherapeutic agents synergistically enhanced cytotoxicity in human and murine melanoma cell lines in ... versus combination treatments was completed using the Agilent microarray system. Single agent and combination therapy effects were tested in vivo in two immunocompetent models of ...
2009 NOV 9 ... According to a study from South Korea, "Cisplatin is a chemotherapeutic agent used in treatment of malignant tumours. However, cisplatin produces various side ...
2009 NOV 23 ... Republic of China, "2-Methoxyestradiol is currently in phase II clinical trials as a chemotherapeutic agent. An LC method with fluorescence detection was developed for determination of ...
2009 NOV 9 ... has numerous anti-carcinogenic properties, but low bioavailability prevents its use in chemotherapeutic applications. One strategy for circumventing this problem has been the creation of ... of cell viability and STAT3 activation, and may thus have potential as a therapeutic agent for cancers expressing high levels of activated STAT3." Hutzen and ...
2009 NOV 16 ... the deliberation that the resistance can be caused during combined administration of chemotherapeutic drugs and Chinese herbal medicines, which induce endoplasmic reticulum stress and/or ... arrest contributed to the resistance mechanism. Curcumin, another G1 arrest-inducing agent in this study, was able to induce a similar resistant effect. Furthermore, the cells ...
2009 NOV 10 ... bursting, varies in the different cells of the ovary. Cisplatin is a broadly used chemotherapeutic agent that results in ovarian damage." "The objective of this study was to test ...
2009 NOV 23 ... research published in the journal Experimental Biology and Medicine, "Paclitaxel is a chemotherapeutic agent used for the treatment of metastatic breast cancer. 2,5,7,8-Tetramethyl-2R-(4R, ...
2009 NOV 16 ... The researchers concluded: "These results suggest protoapigenone is a potential chemotherapeutic agent for lung cancers." Chiu and colleagues published their study in DNA and ...
2009 NOV 9 ... apoptosis in U937 cells; these findings suggest that schisandrin C may be a useful chemotherapeutic agent." Park and colleagues published their study in International Journal of ...
2009 NOV 16 ... a strategy to increase the production of ansamitocin-P3 (AP-3), a clinically promising chemotherapeutic agent. Putative transcriptional regulators asm2, asm29, and asm34 as well as the putative ...
2009 NOV 23 ... There is an urgent need for new treatments for patients with prostate cancer since these chemotherapeutic agents extend survival for only a few months," said Philip Kantoff, M.D., chief ... demonstrated improved efficacy compared with any individual therapy or investigational agent in development to treat prostate cancer. "For patients suffering from ...
