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2009 SEP 28 ... model to study the effect of TAM on T-cell function in vitro, and depleted TAM, using clodronate-containing liposomes, to characterize its role in vivo. TAM, characterized by the ...
2009 SEP 21 ... According to recent research from Taipei, Taiwan, "Clodronate, a halogenated bisphosphonate, can inhibit the growth of human thyroid carcinoma (TC) ...
2009 JUL 13 ... in a macrophage-tropic chemokine receptor, CCR2 or CX3CR1, or in mice treated with clodronate-liposomes (Cl2MDP- lip), which can selectively deplete monocytes/macrophages." ...
2009 SEP 14 ... scaffold was assessed with and without macrophage depletion caused by administration of clodronate-containing liposomes," wrote J.E. Valentin and colleagues, University of Pittsburgh, ...
2009 JUL 27 ... zoledronic acid-induced ApppI formation from IPP was compared with the metabolism of clodronate (a non-N-BP) to adenosine 5'(beta,gamma-dichloromethylene) triphosphate (AppCCl(2)p). ...
2009 NOV 2 ... Council (MRC) PR05 and PR04 randomised controlled trials assessed the use of sodium clodronate, an oral, first-generation bisphosphonate," scientists in London, the United Kingdom ...
2009 JUL 20 ... CT scanning, in patients switching from an early generation bisphosphonate (i.e., oral clodronate or intravenous pamidronate) to intravenous zoledronic acid. with progressive bone ...
2009 AUG 10 ... from breast cancer revealed overall survival benefits for patients receiving clodronate 1600 mg/day compared with placebo; however, combined results from several-trials of ...
2009 NOV 23 ... induced systemic depletion of such cells in the experimental mice by injecting them with clodronate liposomes, which resulted in uncontrolled B. duttonii growth and a one-hundred-fold ...
2009 OCT 12 ... HO-I inhibition with chromium mesoporphyrin IX or Kupffer cell depletion with liposomal clodronate. Bone marrow-derived monocytes were grown from hemopoietic progenitors taken from ...
2009 SEP 14 ... with chemotherapy. Clinical trial results with the early oral bisphosphonate and clodronate were judged to be inconclusive but the recent data with zoledronic acid suggest that ...
2009 AUG 17 ... hepatic hydroxyproline content. We generated CCR2 chimeric mice by the combination of clodronate, irradiation, and bone marrow (BM) transplantation allowing full reconstitution of ...
2009 JUL 13 ... very small amount of QDs detected in the xenograft tumours. Depletion of macrophages by clodronate liposomes did not alter the nonspecific uptake of QDs. In contrast, AVE-1642-conjugated ...
2009 AUG 17 ... skeletal complications. Intravenous pamidronate and zoledronic acid, and oral clodronate are used for the management of MM bone disease," scientists writing in the journal ...
2009 NOV 23 ... operation, followed by intravenous injection of liposomes containing saline vehicle or clodronate, which kills macrophages. Sham-operated myocardium contained some sympathetic axons, few ...
2009 OCT 5 ... IL-6, PTX3, CCL3, and CCL5 levels. By depleting peritoneal resident M phi using clodronate liposomes prior to the application of hCG and the TG trigger, we established that M phi ...
2009 SEP 14 ... endometriotic lesions. in this study, we depleted mouse macrophages by means of either clodronate liposomes or monoclonal antibodies before the injection of syngeneic endometrial tissue. ...
2009 OCT 19 ... trapped in the spleens of L donovani-infected mice. By selective depletion studies using clodronate liposomes, depleting monoclonal antibodies specific for Ly6C/G and Ly6G, and CD11c-DTR ...