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2009 NOV 27 ... concluded: "The absence of the ECT pathway for diacylglycerol utilization at the endoplasmic reticulum triggers increased fatty acid synthesis to support the formation of triacylglycerols ...
2009 NOV 24 ... from Wako, Japan, "Inositol requiring enzyme-1 (IRE1), a protein located on the endoplasmic reticulum (ER) membrane, is highly conserved from yeast to humans. This protein is activated ...
2009 NOV 27 ... Ca2+ (CRAC) channel by first sensing the changes in Ca2+ concentration in the endoplasmic reticulum ([Ca2+](ER)) via its luminal canonical EF-hand motif and subsequently oligomerizing to ...
2009 NOV 24 ... II (GluII) is a glycan-trimming enzyme active on nascent glycoproteins in the endoplasmic reticulum (ER). It trims the middle and innermost glucose residues (Glc2 and Glc1) from N-linked ...
2009 NOV 23 ... "Selenoprotein-S (SELS) is involved in the stress response within the endoplasmic reticulum (ER) and inflammation. Recently, promoter variants in the SELS gene were shown to be ...
2009 NOV 23 ... mechanisms. Proteome analysis revealed significantly regulated proteins associated with endoplasmic reticulum (ER) and mitochondrial stress responses in the epithelium. In contrast to TLR2(-/-) and ...
2009 NOV 24 ... "The GTPase Rab1 regulates endoplasmic reticulum-Golgi and early Golgi traffic. The guanine nucleotide exchange factor (GEF) or factors ...
2009 NOV 23 ... showed an irregular shape with cytoplasmic processes rich in ribosomes and rough endoplasmic reticulum. In these regions, myofibril disorganization and mitochondrial fission were observed. A ...
2009 NOV 24 ... I (COPI) vesicles are involved in the retrograde transport from Golgi apparatus to the endoplasmic reticulum." "The COPI complex is composed of ADP-ribosylation factor 1 and coatomer ...
2009 NOV 24 ... study from Kihara, Japan, "Many tissues have a specific signal transduction system for endoplasmic reticulum (ER) dysfunction; however, the mechanisms underlying the ER stress response in cartilage ...
2009 NOV 24 ... in the journal Nature Cell Biology, "Eukaryotic cells have signalling pathways from the endoplasmic reticulum (ER) to cytosol and nuclei, to avoid excess accumulation of unfolded proteins in the ER. ...
2009 NOV 24 ... tissues. In the tegumental system, there was swelling of the cisternae of granular endoplasmic reticulum and of the mitochondria, with the latter showing signs of breaking down. Autophagic ...
2009 NOV 23 ... represented by RGRSWTY-COOH (termed 'SWTY'), which are capable of overriding an endoplasmic reticulum localization signal and directing membrane proteins to the cell surface via specific ...
2009 NOV 23 ... absence of a signal sequence that can direct the newly synthesized polypeptides to the endoplasmic reticulum. As a result, these cytokines accumulate intracellularly," scientists writing in the ...
2009 NOV 29 ... this lipid accumulates in other locations within the cell, including the membrane of the endoplasmic reticulum (ER). The ER is the structure where proteins are produced. GM1 accumulation in the ER ...
2009 NOV 23 ... scientists in Jinan, People's Republic of China report. "The endoplasmic reticulum (ER) has been shown to be a central organelle, and it is the location of CYP7A1 in ...
2009 NOV 23 ... Scientists discuss in 'Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells' new findings in life sciences. ...
2009 NOV 23 ... phosphorylation, whereas atypical antipsychotics affected genes associated with golgi/endoplasmic reticulum and cytoplasm transport. Comparison between typical antipsychotics and atypical ...
2009 NOV 27 ... United States report."We hypothesized that domain interaction elicits an endoplasmic reticulum (ER) stress in astrocytes and an unfolded protein response that targets Arg-61 apoE for ...