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2009 NOV 24 ... According to recent research from the United States, "The ectodomain shedding of epidermal growth factor receptor (EGFR) ligands, such as amphiregulin (AREG), by ADAMs (A Disintegrin And ...
2009 NOV 23 ... of Proteins with F-18 Exemplified by Quantitative Positron Emission Tomography of Human Epidermal Growth Factor Receptor 2. Journal of Medicinal Chemistry, 2009;52(19):5816-5825). For more ...
2009 NOV 23 ... "Transforming growth factor (TGF)-alpha and its receptor, the epidermal growth factor receptor, are induced after lung injury and are associated with remodeling in chronic pulmonary ...
2009 NOV 23 ... constriction, both in the intact mouse lung and a cell culture model, activate the epidermal growth factor receptor (EGFR), a known modulator of mucin expression in airway epithelial cells." ...
2009 NOV 23 ... We investigated GBM cell killing by a novel drug combination involving DT-EGF, an Epidermal Growth Factor Receptor-targeted bacterial toxin, and Tumor Necrosis Factor-Related Apoptosis Inducing Ligand ...
2009 NOV 23 ... recently reported that TAK1 regulates the transient phosphorylation and endocytosis of epidermal growth factor receptor (EGFR) in a tyrosine kinase activity-independent manner," scientists in Toyama, Japan ...
2009 NOV 23 ... hepatocelular carcinomas (HCC) in humans and dogs, our work describes the expression of epidermal growth factor receptor (EGFr), cytokeratine 19 (CK19), vascular endothelial growth factor (VEGF) and ...
2009 NOV 23 ... in patients with non-small cell lung cancer (NSCLC)." "The expression of epidermal growth factor receptor (EGFR), excision repair cross-complementing (ERCC1), vascular-endothelial growth factor ...
2009 NOV 23 ... researchers in the United States report. "We previously found that epidermal growth factor receptor (EGFR) inhibitors induce acute myeloid leukemia (AML) differentiation via a non-EGFR ...
2009 NOV 23 ... factor domain of ErbB receptor ligands. S100A4 selectively interacted with a number of epidermal growth factor receptor (EGFR) ligands, demonstrating highest affinity for amphiregulin. Importantly, we found ...
2009 NOV 23 ... "Expression of the human epidermal growth factor receptor 2 (HER2) is amplified in 25% to 30% of breast cancers and has been associated with an ...
2009 NOV 23 ... by 2.2 +/- 0.3-fold. 20-HETE and 5,14-20-HEDE also promoted activation (Y1086) of epidermal growth factor receptor (EGFR; Y1086) by 1.9 +/- 0.2- and 2.5 +/- 0.2-fold, respectively. These effects were ...
2009 NOV 23 ... significantly decreased mRNA expressions of Bcl2, cyclin D1, pS2, ER alpha, and ER beta, epidermal growth factor receptor, and insulin-like growth factor receptor. FS also reduced human...
2009 NOV 23 ... "Both the epidermal growth factor receptor signaling pathway and microRNA (miRNA) play an important role in lung cancer development ...
2009 NOV 23 ... receptor tyrosine kinase inhibitor of vascular endothelial growth factor and epidermal growth factor receptor, on paclitaxel (PTX) tumor distribution and antitumor activity in xenograft models of ...
2009 NOV 23 ... factor (EGF)-SubA, combining EGF and SubA, is highly toxic to growing and confluent epidermal growth factor receptor-expressing cancer cells, and its cytotoxicity is mediated by a remarkably rapid cleavage ...
2009 NOV 23 ... Current study results from the report, 'Comparison of global versus epidermal growth factor receptor pathway profiling for prediction of lapatinib sensitivity in bladder cancer,' have been ...
2009 NOV 23 ... and advisory firms for pharmaceutical and healthcare issues, finds that, in 2008, human epidermal growth factor receptor 2 (HER2) targeting therapies -- which include Roche/Chugai's Herceptin and ...
2009 NOV 23 ... results, 'A case report of inflammatory nonscarring alopecia associated with the epidermal growth factor receptor inhibitor erlotinib,' are detailed in a study published in Journal of Cutaneous ...
2009 NOV 23 ... of GnRH-II expression in these cells remains unclear. We now demonstrate that epidermalgrowthfactor (EGF) increases GnRH-II mRNA levels in several human ovarian carcinoma ... GnRH-II promoter activity in OVCAR-3 cells in a dose-dependent manner, whereas an EGF receptor inhibitor (AG148) abolishes EGF-induced increases in GnRH-II promoter activity and ...
