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2009 NOV 29 ... lab, zeroed in on one of the two receptors that mediate estrogen function in cells - estrogen receptor (ER) alpha. He crossed his HPV mice with mice in which ER alpha had been knocked out, ...
2009 NOV 27 ... water effluents contain a complex mixture of substances which are known to bind to the estrogen receptor (ER) and antagonize the androgen receptor (AR). Short-chain petrogenic alkylphenols have ...
2009 NOV 25 ... "The soy isoflavone metabolite, S-(-)equol, has selective affinity for estrogen receptor (ER),G and also antagonizes in vivo the action of dihydrotestosterone. It is therefore ...
2009 NOV 23 ... to breast carcinogenesis is highlighted by evidence indicating that use of combined estrogen-progesterone therapy (EPT) is more strongly related to breast cancer risk than is use of ... Data detailed in 'Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk' have ...
2009 NOV 23 ... of the biological effects of estrogens in the reproductive tract are mediated by estrogen receptor (ER)alpha, which regulates transcription by several mechanisms. Because the ...
2009 NOV 23 ... breast cancer risk modification of low to moderate radiation dose by polymorphic estrogen metabolism-related gene variants has not been routinely investigated." ... candidate variants in 12 genes involved in steroid metabolism, catabolism, binding, or receptor functions in a study of 859 cases and 1,083 controls within the US radiologic ...
2009 NOV 23 ... with low bone mineral density (BMD)." "Vitamin D receptor (VDR) and estrogen receptor (ER) gene polymorphisms were the first to be studied. Some studies have shown a possible ...
2009 NOV 23 ... proliferation of cervical cancer cells, but its effect is not mediated by androgen or estrogen receptor pathways," wrote R.A. Giron and colleagues. The researchers concluded: ...
2009 NOV 23 ... Comprehensive Cancer Network has recommended that the immunohistochemical expression of estrogen (ER) and/or progesterone (PR) receptors in a carcinoma of unknown primary can be used to ... study in Applied Immunohistochemistry & Molecular Morphology (Estrogen and Progesterone Receptor Expression is not Always Specific for Mammary and Gynecologic Carcinomas A Tissue ...
2009 NOV 23 ... enhanced the expression of Bax and cytochrome c release and suppressed the expression of estrogen receptor in tumor cells. Treatment with curcumin inhibited the expression of Bcl-2 in tumor cells ...
2009 NOV 23 ... each with an implanted 17 beta-estradiol (E2) pellet (0.36 mg), were injected with human estrogen receptor (ER) positive breast cancer cells (MCF-7)." "When tumors were ...
2009 NOV 23 ... According to recent research from the United States, "Mice lacking estrogen receptor alpha in the pituitary gonadotroph (PitEsr1KO) were generated to determine the ...
2009 NOV 23 ... cases were invasive ductal carcinomas. Q score >or=6 was identified in five cases for estrogen receptor and four for progesterone receptor. Mean Q score started to decline at the 2 h mark for ...
2009 NOV 23 ... "We showed that 17 beta-estradiol (E-2) favors pancreatic beta-cell survival via the estrogen receptor-alpha (ER alpha) in mice. E-2 activates nuclear estrogen receptors via an estrogen ...
2009 NOV 23 ... breast carcinomas arising in postmenopausal women are estrogen dependent or positive for estrogen receptor (ER) in carcinoma cells despite markedly low plasma or circulating estrogen ...
2009 NOV 23 ... it emerges that aromatase is a target of cross talk between growth factor receptors and estrogen receptor alpha signaling," wrote S. Catalano and colleagues, University of Calabria. ...
2009 NOV 23 ... involvement of AP-1 Fra-1/c-Jun and NF-kappa B p65/RelB members, but not of the alpha estrogen receptor in promoting chromatin accessibility and transcription across the IL-6 gene promoter in ...
2009 NOV 23 ... for premenstrual mastalgia,' are discussed in a new report. "Toremifene, a selective estrogen receptor modulator, has been shown to be effective in alleviating premenstrual breast pain. ...
2009 NOV 23 ... "Traditional prognostic markers for breast cancer include estrogen receptor (ER), progesterone receptor (ER) and HER2/neu. Negative staining for these three markers ...
2009 NOV 24 ... "This study tested the hypothesis that the estrogen receptor (ESR) pathway, androgen receptor (AR) pathway, or both mediate estrogen-induced ...
