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2009 NOV 29 ... he says.Chung turned to an ER alpha blocker used to treat breast cancer, fulvestrant, and tested it on the HPV-positive mice with cervical cancer. After one month, he found ...
2009 JUL 13 ... treatment in oestrogen- and/or progesterone-receptor (ER/PgR) positive breast cancer. Fulvestrant is a pure ER-antagonist," scientists in Vienna, Austria report. "We ...
2009 SEP 28 ... we performed a cost-utility analysis by comparing treatment sequences including/omitting fulvestrant in a hypothetical population of hormone receptor-positive (HR+) postmenopausal women ...
2009 OCT 19 ... ER alpha-positive MCF7 cells, which was abrogated by pretreatment with the antiestrogen fulvestrant (ICI 182,780). Analysis of UGT1A4 upstream regions using luciferase reporter assays ...
2009 OCT 19 ... AXL expression. Furthermore, small interfering RNA to AXL, estrogen deprivation, or fulvestrant, an ER antagonist, decreases AXL expression and restores sensitivity to lapatinib in ...
2009 SEP 28 ... (The Evaluation of Faslodex versus Exemestane Clinical Trial) examining the efficacy of fulvestrant and exemestane in patients with or without VM." "EFECT is a randomised, ...
2009 NOV 1 ... monoclonal sublines that survived 21-day exposure to tamoxifen (T-series sublines) or fulvestrant (F-series sublines) and sublines unselected by drugs (U-series)." "All ...
2009 JUL 6 ... phosphatidylinositol-3 kinase (PI3K) and AKT activities, resistance to tamoxifen and fulvestrant, and hormone-independent growth. PTEN knockdown induced the up-regulation of ER ...
2009 SEP 28 ... "This prospective study assessed the endometrial effects of fulvestrant, a pure estrogen-receptor antagonist, in postmenopausal women with breast cancer. This ...
2009 AUG 31 ... alpha expression (RQ=1.14 vs. RQ=0.65, p<0.001). In stimulation assays, tamoxifen and fulvestrant increased ERa expression to RQ=1.51 (p=0.01) and RQ=1.42 (p <0.001), respectively, ...
2009 AUG 10 ... and aromatase inhibition; and antagonism and downregulation of ER by the antiestrogen fulvestrant," scientists in London, the United Kingdom report. "Each of these ...
2009 JUL 6 ... (n=8) or bovine serum albumin (BSA)-conjugated 17beta-oestradiol (n=8). Fulvestrant, an oestrogen receptor antagonist, was added to some baths (n=8). Other strips were ...
2009 JUL 21 ... GA or RAD could inhibit this association. Blocking estrogen receptors with ICI182780 (fulvestrant) also prevented this association," wrote G.C. Han and colleagues, Texas A&M University. ...
Subject: Pharmacology and Experimental Therapeutics
2009 JUN 29 ... According to recent research from London, the United Kingdom, "Fulvestrant is a pure estrogen receptor (ER) antagonist with no agonist effects. We describe the ...
