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2009 DEC 1 ... de novo transcriptome sequencing and analysis, enabling a comprehensive picture of the gene space of nearly any organism, even previously uncharacterized species. "We ... of the GS FLX Titanium series chemistry - transcriptome sequencing and amplicon (PCR product) sequencing. Additional product updates highlight the company's continued efforts to ...
2009 DEC 3 ... the United States and Asia, is an international provider of DNA sequencing services, gene synthesis, DNA/siRNA synthesis products and bioinformatic services for academic and ... SCIENCES, GS FLX, and NIMBLEGEN are trademarks of Roche. Other brands or product names are trademarks of their respective holders. Keywords: Biotechnology, ...
2009 DEC 1 ... access to GeneGo's manually curated databases. Users can query the database with gene, protein, compound, drug names, diseases, and processes, pathological or toxic ... the leading systems biology tools company, announced the release of a stand alone search product, Eureka! It provides a simple one-button one-window access to GeneGo's manually curated ...
2009 NOV 30 ... drug discovery and development programs are based on advanced cell-based assays, gene-expression tools, ultra-high throughput screening and one of the world's largest ... this release. These statements include those regarding data analysis and evaluation of product candidates and plans for continued development of product candidates that are the ...
2009 NOV 30 ... functioning genes that encode copper-containing amine oxidases. The product of the AOC1 gene is a so-called diamine oxidase (hDAO), named for its substrate preference for diamines, ...
2009 DEC 1 ... microsatellite markers. Mutation analysis was done by direct sequencing of the candidate gene GRK1 located in the region. The segregation of a novel mutation in the family and the ... 1 of GRK1. This mutation is predicted to result in premature termination of the protein product, thereby affecting the phototransduction cascade. A clinical reappraisal of the family ...
2009 NOV 30 ... HS patient who was found to be carrying compound heterozygous mutations in the LIPH gene: a 7-bp frameshift duplication (c.403_409dup; p.Gln137HisfsX1) and a recently reported ... mutations and provides biochemical evidence for the important role of lipase H and its product LPA in human hair growth." Pasternack and colleagues published their study ...
2009 NOV 30 ... the latter processes are largely unknown. We previously discovered that a bi-functional gene, Spag16, is essential for spermatogenesis. SPAG16S, the 35 kDa, testis-specific isoform ... isoform derived from the Spag16 gene, was found to bind to meiosis expressed gene 1 product (MEIG1), a protein originally thought to play a role in meiosis. We inactivated the ...
2009 DEC 1 ... different time in evolution, indicating that each represents a distinct function of the gene product and that the AGL6-like genes are pleiotropic. Expression in the inner integument of the ...
2009 NOV 30 ... in the methanogenic archaea. This intermediate is produced from GTP by MptA (MJ0775 gene product), a new class of GTP cyclohydrolase I [Grochowski, L. L., Xu, H., Leung, K., and White, ...
2009 NOV 30 ... Bacillus subtilis, the yoxA and dacC genes were proposed to form an operon. The yoxA gene was overexpressed in Escherichia coli and its product fused to a polyhistidine tag was ...
2009 NOV 30 ... "The molecular mass of the mature form was calculated to be 45,520 Da. The gene product expressed in Pichia pastoris specifically hydrolyzed beta-(1 -> ...
2009 NOV 30 ... dysplasia syndrome (ODDD) with a heterozygous mutation in GJA1 (connexin 43) gene. A 9-year-old girl visited our hospital complaining of visual disturbances." ... We amplified GJA1 exon 2 from her genomic DNA by the PCR method, and sequenced the product using the dye terminator method. S5C (c. 13A > T), a novel mutation in exon 2 of ...
2009 NOV 30 ... among the genes that play a relevant role in bacterium colonization and persistence. The gene has been cloned and its product, protein TenA, has been expressed and purified." ...
2009 NOV 30 ... GPCR, G-protein-coupled receptor), the protein product of the ocular albinism type 1 gene, encodes a pigment-cell-specific GPCR that localizes intracellularly to melanosomes. OA1 ...
2009 NOV 30 ... which are coded for by a set of genes that are often found adjacent to the structural gene, nirS, for cytochrome cd(1) nitrite reductase. NirE, the product of the first gene in ...
2009 NOV 30 ... for the immune responses; while the presence of a transgene product (or foreign gene product produced by host cells) was not immunogenic. Intriguingly, preimmunization with ...
2009 NOV 30 ... understanding of mechanisms underlying HAD." "In this study we integrate gene expression data from uninfected and SIV-infected hippocampus with a human protein ... be downregulated in differentiated human neuroblastoma cells by treatment with CCL8, a product of activated microglia. Integration of expression data with protein interaction data to ...
2009 NOV 30 ... Syndrome, Biotechnology, Biotechnology Business, Biotechnology Company, Cardiology, Gene Therapy, Genetics, Genomics, Genzyme Corporation, HIV, HIV/AIDS Vaccine, Health, Heart ... recognized in the first half of 2009 in connection with its delivery of MYDICAR® product candidate to its partner Celladon Corporation. Revenue for the third ...
2009 NOV 30 ... of state-of-the-art genetic analysis systems, announced a new, innovative service for gene-expression profiling of thousands of genes using the SmartChip™ Real-Time PCR ... scientists involved in the discovery and validation of molecular biomarkers. The initial product to be run on the SmartChip platform is the SmartChip Human Oncology Gene Panel that ...
