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2009 NOV 24 ... "PIWI-interacting RNAs (piRNAs) silence retrotransposons in Drosophila germ lines by associating with the PIWI proteins Argonaute 3 (AGO3), Aubergine (Aub) and ... remains elusive. Here we analysed piRNA processing in a Drosophila ovarian somatic cell line where Piwi, but not Aub or AGO3, is expressed; thus, only the primary piRNAs exist. ...
2009 NOV 23 ... the expression of cGMP-hydrolyzing phosphodiesterases (PDEs) in the somatic and germ cell compartments of the mouse ovarian follicle and demonstrate that PDE5 is preferentially ...
2009 NOV 27 ... heteroclitic peptide, ELAGIGILTV, bound to HLA-A*0201 (A2ELA). Unusually, the TRAV12-2 germ line-encoded regions of the TCR dominate the major atomic contacts with the peptide at ... by human leukocyte antigen (HLA)A* 0201, are exceptionally common in the naive T-cell repertoire. Remarkably, the TRAV12-2 gene is used to encode the T-cell receptor ...
2009 NOV 23 ... According to recent research from Madrid, Spain, "Testicular germ cell tumors sometimes regress spontaneously and manifest exclusively by metastasis. We report ...
2009 NOV 23 ... to rESCs. Moreover, unlike epiblast and EpiSCs, rESCs contribute to somatic tissues and germ cells in chimaeras," wrote S.Q. Bao and colleagues, University of Cambridge. ... with uniform expression of N-cadherin and inactive X chromosome to ES-cell-like cells (rESCs) in response to LIF-STAT3 signalling. Cultured epiblast cells overcome ...
2009 NOV 23 ... "Several, but not all, studies have observed increased risks of testicular germ cell cancer (TGCC) associated with bicycling and other recreational activities. To further ...
2009 NOV 23 ... of telomeres (ALT). The ALT phenotype, relatively common in certain sarcomas and germ cell tumors, is very rare in carcinomas," scientists in the United States report. ...
2009 NOV 17 ... studies have implicated RNA regulation, the mechanism that normally prevents the loss of germ cell identity remains unexplained. In C. elegans, a teratoma is induced in the absence of the ...
2009 NOV 17 ... through all stages of axis elongation. These data challenge the paradigm that the three germ layers, formed by gastrulation, constitute the primary branchpoints in differentiation ... research from Paris, France, "Clonal lineage information is fundamental in revealing cell fate choices. Using genetic single-cell labeling in utero, we investigated lineage ...
2009 NOV 23 ... mediators by Gpr43(-/-) immune cells, and increased immune cell recruitment. Germ-free mice, which are devoid of bacteria and express little or no SCFAs, showed a similar ...
2009 NOV 23 ... of several pediatric malignancies. We examined this relationship in a study of childhood germ cell tumors (GCT)," investigators in the United States report. "included 278 ...
2009 NOV 17 ... development from a single cell, short-term and long-term genetic cotransmission, germ-soma separation and membership in the same species." Queller and ...
2009 NOV 24 ... connections, termed intercellular bridges (ring canals). In forficuloid earwigs, female germ cell cysts are composed of two cells only: the pro-oocte and pronurse cells. We show that in ...
2009 NOV 16 ... have been published. "The establishment of sexual identity is a crucial step of germ cell development in sexually reproducing organisms. Sex determination in the germline is ...
2009 NOV 16 ... ultrastructure into a primitive archetype and induced stem cell markers generating 3-germ layers, all qualifiers of acquired pluripotency. Three-factor induced iPS (3F-iPS) ...
2009 NOV 16 ... linked to the production of few or no oocytes or sperm. Yet, our understanding of human germ cell development is poor, at least in part due to the inaccessibility of early stages to ...
2009 NOV 23 ... "Germ cells are sensitive to genotoxins, and ovarian failure and infertility are major side ... the c-Abl-TAp63 pathway activated by chemotherapeutic DNA-damaging drugs in model human cell lines and in mouse oocytes and its role in cell death," investigators in Rome, Italy ...
2009 NOV 23 ... concentration to be able to address the specific INSL3 receptors (RXFP2) on post-meiotic germ cells and in the epididymis." Anandivell and colleagues published their ... According to recent research from Adelaide, Australia, "The Leydig cell-specific factor insulin-like peptide 3 (INSL3) is involved in testicular descent during ...
2009 NOV 16 ... disruption of the seminiferous epithelium with an apparent spermatocytic arrest of the germ cell population. in the present study utilizing a chromosomal spread technique, we determined ...
