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2009 NOV 17 ... "We present a case of Brooke-Spiegler syndrome with a germline deep intronic mutation in the CYLD gene leading to intronic exonization. Additionally, ...
2009 NOV 23 ... of Oxford. The researchers concluded: "These results suggest that although germline variation in CYP19A1 characterized by the htSNPs produces measurable differences in sex ...
2009 NOV 16 ... regulation requires two critical cis-acting imprinting centres, carrying different germline epigenetic marks and mediating imprinted expression in the proximal and distal ...
2009 NOV 23 ... to recent research published in the journal Genetic Testing and Molecular Biomarkers, "Germline mutations in the BRCA1/2 genes contribute to most of inherited breast and ovarian ...
2009 NOV 12 ... silencing and are mainly restricted to gonadal tissues. Endo-siRNAs are found in both germline and somatic tissues. These similar to 21-nt RNAs are produced by a distinct Dicer, ...
2009 NOV 10 ... Two affected sisters had a mutation not detectable in their parents, supporting germline mosaicism. Their father had undergone radiation for testicular cancer in the past. Two ...
2009 NOV 17 ... in Reproduction (Expression pattern of meiosis associated SYCP family members during germline development in chickens. Reproduction, 2009;138(3):483-492). For additional ...
2009 NOV 23 ... sisters affected. Investigations. At 58 years of age, the patient underwent BRCA2 germline testing and was found to be a mutation carrier. Following post-test counseling, he was ...
2009 NOV 24 ... species, gametogenesis starts with the formation of cysts (clusters) of sibling germline cells. Cysts originate as the result of mitotic divisions of a specialized...
2009 NOV 16 ... heterozygous for the somatic JAK2(N542-E543del) mutation and a previously unreported germline mutation within the SH2 domain of SOCS3 (F136L). Interestingly, the SOCS3(F136L) ...
2009 NOV 17 ... of this behavior, however." "We used an HIV-based lentivirus to produce germline transgenic zebra finches. The lentivirus encoded the GFP regulated by the human ...
2009 NOV 16 ... in less developed vertebrates, pluripotent stem cells can be generated from the female germline even in mammals, via parthenogenetic activation of oocytes. Recently, testis-derived ...
2009 NOV 23 ... of cancer of the large bowel, extracolonic body sites and brain. It is caused by germline mutations in genes encoding for components of the DNA mismatch repair system," ...
2009 NOV 16 ... The researchers concluded: "Our case report presents the fourth case in which a de novo germline mutation in a BRCA1/2 gene has been identified." Marshall and colleagues ...
2009 NOV 16 ... and later found in the germ line of a familial GIST cohort. A mouse model harbouring a germline Kit K641E mutant was created to model familial GIST. The expression profile was ...
2009 NOV 16 ... study results from the report, 'The establishment of sexual identity in the Drosophila germline,' have been published. "The establishment of sexual identity is a crucial step of germ ...
2009 NOV 10 ... stably maintained during subsequent spermiogenesis. Here we characterize XCI in the male germline and female soma of the marsupial Monodelphis domestica. Contrary to the meiotic ...
2009 NOV 10 ... protein, Rhino, is required for piRNA generation and transposon silencing in Drosophila germline cells," wrote M. Halic and colleagues, Harvard University, Medical Department. ...
2009 NOV 16 ... to cancer susceptibility and sporadic tumorigenesis. We resequenced CLSPN from the germline of selected cancer families with a history of breast cancer (n = 25) or a multicancer ...
