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2009 NOV 16 ... partnership with Pfizer, the development of lead candidate CDX-110 in Phase 2 studies in glioblastoma multiforme. CDX-110 is an immunotherapy that targets the tumor specific molecule called EGFRvIII, a ...
2009 NOV 9 ... phase 2 clinical data which show that XL184 demonstrated activity in patients with glioblastoma multiforme (GBM), the most common and aggressive form of brain cancer. The data from ...
2009 NOV 16 ... results from a cutting-edge research study that treated the aggressive brain tumors glioblastoma multiforme (GBM) using a novel type of imaging called MR spectroscopy coupled with high dose ...
2009 NOV 9 ... Company's dendritic-cell based cancer vaccine product candidate for the treatment of glioblastoma multiforme (GBM). These new data showed a greater progression-free survival time in patients ...
2009 NOV 9 ... According to recent research from the United States, "Glioblastoma multiforme (GBM) is the most common and lethal primary brain tumor variant. It exhibits ...
2009 NOV 9 ... AKT/mammalian target of Rapamycin (mTOR) signaling pathway plays a critical role in glioblastoma multiforme (GBM) oncogenesis due to activation of AKT. We studied two distinct complexes, mTOR ...
2009 NOV 9 ... the cellular and biochemical functions of NDRG4 in the context of astrocytes and glioblastoma multiforme (GBM) cells. We show that, in contrast to NDRG2, NDRG4 expression is elevated in GBM and ...
2009 NOV 16 ... we investigated the effect of danthron on the cell migration and invasion of human brain glioblastoma multiforme GBM 8401. cells in vitro. The changes of migration and invasion of GBM 8401 cells after ...
2009 NOV 23 ... unique protein identifications was obtained for the proteome of a human brain tumor (glioblastoma multiforme) by combining the results of two complementary analytical strategies based on ...
2009 NOV 16 ... to a study from Athens, Greece, "Phase I-II studies indicate that imatinib is active in glioblastoma multiforme. To better understand the molecular and clinical effects of imatinib in...
2009 NOV 23 ... (five women, four men) with histologically confirmed brain tumors (four metastases, one glioblastoma multiforme, three meningiomas, and one lymphoma)." "Fractional anisotropy (FA), ...
2009 NOV 16 ... the United States, "Anaplastic astrocytoma (AA) and its more aggressive counterpart, glioblastoma multiforme (GBM), are the most common intrinsic brain tumors in adults and are almost universally ...
2009 NOV 23 ... examine such association in a large series of cases. The study population includes 814 glioblastoma multiforme cases that were newly diagnosed, histologically confirmed, aged 20 or older, and ...
2009 NOV 16 ... followed by monthly temozolomide (TMZ) is the standard of care for patients with glioblastoma multiforme (GBM). reports have identified GBM patients who experienced transient radiological ...
2009 NOV 23 ... Therapy Oncology Group (RTOG) embarked on a phase I/II study of patients suffering from glioblastoma multiforme (protocol 98-03) to assess the impact of dose escalation with 3-D conformal techniques. ...
2009 NOV 23 ... Finally, IRF9 overexpression facilitated IFN-alpha-induced apoptosis in T98G (human glioblastoma multiforme) cells, which were resistant to IFN-alpha," wrote T. Tsuno and colleagues, National ...
2009 NOV 23 ... the United States, "Oncolytic herpes simplex viruses (HSV) hold promise for therapy of glioblastoma multiforme (GBM) resistant to traditional therapies. We examined the ability of genetically ...
