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2009 NOV 2 ... to affect Env by significantly decreasing its steady-state levels, its processing into gp120/gp41, and its mass by inducing glycan removal in a manner dependent on its native signal ...
2009 NOV 16 ... virion membrane and the target cell plasma membrane. Env is composed of two subunits: gp120, which binds to CD4 and the coreceptor, and gp41, which is triggered upon coreceptor ...
2009 NOV 16 ... treatment in rodents. Utilizing a rodent model that incorporates the viral coat protein, gp120, and the NRTI, 2'3'-dideoxycytidine (ddC), we examined the degree to which chemokine ...
2009 OCT 19 ... in Paul's laboratory used a chemically-activated form of the HIV envelope protein gp120 to stimulate the production of mouse monoclonal antibodies that block infection of ...
Subject: University of Texas Health Science Center at Houston
2009 OCT 19 ... HxB2 with little effect on the primary virus, Du151. Adsorption with Du151 monomeric gp120 reduced neutralizing activity to some extent in most plasma samples when tested against ...
2009 OCT 5 ... cardiomyopathy. Potential mechanisms include direct effects of HIV proteins, including gp120," scientists writing in the journal Cardiovascular Toxicology report. "We ...
2009 NOV 9 ... likely by blocking HIV-1 interaction with target cells, i.e., the interaction between gp120 and CD4/CCR5 or gp120 and CD4/CXCR4 and point to the ...
2009 OCT 19 ... "The envelope protein of human immunodeficiency virus type 1 (HIV-1)-glycoprotein 120 (gp120)-has been demonstrated to dysregulate T cell function in vitro. We obtained autopsy ...
2009 OCT 13 ... Very strong selection for sequons with both Thr and Ser in glycoprotein of M-r 120,000 (gp120) of HIV and related retroviruses results from this same mechanism, as well as amino acid ...
2009 NOV 1 ... enhances HIV macrophage tropism, possibly by exposing a region on the outer domain of gp120 that is initially recognized by CD4," wrote R.L. Dunfee and colleagues. ...
2009 NOV 16 ... According to a study from Grenoble, France, "The HIV-1 envelope, gp120, which features the binding determinants for both CD4 and coreceptor recognition, is key ...
2009 OCT 12 ... particles (HIV-VLPs), produced in a baculovirus expression system and presenting a gp120 molecule from a Ugandan HIV-1 isolate of clade A (HIV-VLPAs), induce maturation and ...
2009 NOV 9 ... in vitro anti-HIV activity by binding to high-mannose ( Man) type glycans (HMTGs) of gp120, an envelope glycoprotein of HIV. AH contains 114 aa and consists of three segments, all ...
2009 NOV 2 ... "The extensive glycosylation of HIV-1 envelope proteins (Envs), gp120/gp41, is known to play an important role in evasion of host immune response by masking ...
2009 NOV 2 ... on trimeric Envelope protein and spans conserved regions of variable loops of the gp120 subunit," wrote L.M. Walker and colleagues. The researchers concluded: ...
2009 NOV 16 ... study examines the secretion of normal platelets after exposure to recombinant HIV-1(MN) gp120 or gp41 peptides. There was a modest but significant decrease in regulated upon ...
