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2009 NOV 2 ... Env by significantly decreasing its steady-state levels, its processing into gp120/gp41, and its mass by inducing glycan removal in a manner dependent on its native signal ...
2009 OCT 19 ... transmission. Mucosal immunoglobulin A (IgA) antibody specific for HIV-1 envelope gp41 subunit is one correlate of protection in individuals who are highly sexually exposed to ...
2009 NOV 16 ... Env is composed of two subunits: gp120, which binds to CD4 and the coreceptor, and gp41, which is triggered upon coreceptor binding to promote the membrane fusion reaction," ...
2009 NOV 1 ... According to recent research from Rehovot, Israel, "Peptide inhibitors derived from HIV-gp41 envelope protein play a pivotal role in deciphering the molecular mechanism of HIV-cell ...
2009 OCT 5 ... and prevented virus spread." "Also, the expression of the HIV-1 gp41 gene in HeLa cells was inhibited by complementary short interfering DNA. We showed that ...
2009 OCT 12 ... by cell surface-expressed HIV-1 Env correlated with the fusogenic properties of the gp41 subunit of Env. A crucial step in HIV gp41-mediated ...
2009 NOV 2 ... of neutralizing antibodies 2F5 and 4E10 to human immunodeficiency virus type 1 (HIV-1) gp41 involves both the viral membrane and gp41 membrane ...
2009 SEP 21 ... at risk for infection with non-subtype B strains. Analysis of gag p24, pol IN, and env gp41 IDR revealed the presence of five subtypes (A, B, C, D, H), CRF02_AG, and four unique ...
2009 SEP 21 ... "The hydrophobic pocket within the coiled coil domain of HIV-1 gp41 is considered to be a hot-spot suitable for small molecule intervention of fusion, ...
2009 NOV 2 ... infection and is catalyzed by the binding of the fusion peptide domain (HFP) of the HIV gp41 protein to the host cell membrane. The HFP by itself induces vesicle fusion and is a ...
2009 SEP 21 ... all contain different functional domains and have different primary binding sites in gp41. As such, they may work cooperatively to inhibit gp41 ...
2009 OCT 19 ... external region (MPER) of the human immunodeficiency virus (HIV) envelope glycoprotein (gp41) is critical for viral fusion and infectivity and is the target of three of the five ...
2009 SEP 21 ... According to recent research from the United States, "We analyzed HIV gp41 from 195 men in the United States who were HIV-1 infected between 1999 and 2002, before ...
2009 NOV 2 ... and/or entry step. In addition, a putative GBV-C E2 fusion peptide interferes with HIV gp41 peptide oligomerization required for HIV-1 fusion, further suggesting that GBV-C E2 may ...
2009 NOV 2 ... beta-amino acid residues in the context of a polypeptide sequence from the HIV protein gp41, which represents an excellent testbed because of the wealth of available structural and ...
2009 SEP 21 ... underwent neurological, neuropsychological, and functional assessments, and gag and gp41 regions were subtyped. Subtype assignments were generated by sequence analysis using a ...
2009 NOV 2 ... "The extensive glycosylation of HIV-1 envelope proteins (Envs), gp120/gp41, is known to play an important role in evasion of host immune response by masking key ...
2009 NOV 16 ... for the majority of the protein-coding regions of the HIV-1 variants in LSC63 (except gp41, nef, and the 3' half of pol), the genetic distances between the infecting viruses and ...
2009 NOV 16 ... the secretion of normal platelets after exposure to recombinant HIV-1(MN) gp120 or gp41 peptides. There was a modest but significant decrease in regulated upon activation, ...
