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2009 NOV 16 ... acid. These under-excretors of uric acid make up approximately 90% of the patients with hyperuricemia and gout, and are the primary target population for RDEA594," added Dr. Quart. ...
2009 OCT 12 ... 2a, proof-of-concept study of RDEA594, its lead product candidate for the treatment of hyperuricemia and gout, at the 2009 American College of Rheumatology (ACR) / Association of ...
2009 OCT 12 ... Professor of Medicine. "The longstanding unmet need for innovative therapies to reduce hyperuricemia is now being addressed by novel agents, among them BCX4208, that act as novel ...
2009 SEP 7 ... function, but also other CyA-associated side effects, such as hypercholesterolemia, hyperuricemia, hypertension and diabetes.." Pons and colleagues published their study in ...
2009 OCT 12 ... is developing Uricase-PEG 20 for the treatment of refractory gout and the management of hyperuricemia associated with tumor lysis syndrome. About EnzymeRx EnzymeRx. LLC is a private, ...
2009 NOV 2 ... of TLS. Patients considered at high risk for TLS either had an elevated level of PUA (hyperuricemia) due to a malignancy, or were diagnosed with a very aggressive hematologic malignancy ...
2009 NOV 2 ... membranes of the distal nephron. Mice with systemic knockout of Glut9 display moderate hyperuricemia, massive hyperuricosuria, and an early-onset nephropathy, characterized by obstructive ...
2009 SEP 28 ... control Long-Evans Tokushima Ohtsuka (LETO) rats were used to generate a model for acute hyperuricemia. Upon the onset of insulin resistance OLETF rats were feed with high-purine diet, and ...
2009 NOV 16 ... National Institutes of Health. The researchers concluded: "First-trimester hyperuricemia is associated with an increased risk of developing GDM, independent of body mass ...
2009 SEP 28 ... recruited. Cases under medication for hypertension, hyperlipidemia, diabetes mellitus, hyperuricemia, or cardiovascular diseases were excluded from the study. Cases suffering from chronic ...
2009 NOV 16 ... (kappa = 0.68). The prevalence of anemia, hypocalcemia, hyperphosphatemia (HF), hyperuricemia (HU), and systemic arterial hypertension (SAH) was 10.6%, 7.6%, 10.3%, 54%, and 73.4% ...
2009 NOV 3 ... from Tunis, Tunisia, "Pyrazinamide can have adverse effects such as hepatic toxicity, hyperuricemia or digestive disorders. In rare cases, alterations in taste and smell function have been ...
2009 SEP 21 ... based on the number of risk factors (hypertension, hyperglycemia, dyslipidemia, and hyperuricemia). The relationship between obesity and risk factors and the relationship between obesity ...
2009 SEP 7 ... scientists in the United States conducted a study "To assess the association between hyperuricemia and risk of stroke incidence and mortality because...
2009 OCT 12 ... families with the autosomal-dominant inheritance of early onset anemia, hypouricosuric hyperuricemia, progressive kidney failure, and mutations resulting either in the deletion (p.Leu16del) ...
2009 OCT 12 ... for both C2 and C0 levels were significant as predictors of hyperkalemia (P < .001), hyperuricemia (P = .001), hypercholesterolemia (P < .05), and high systolic blood pressure (P < ...
2009 OCT 5 ... age 20-49 yrs) who underwent health examinations at this hospital between 2000 and 2007. Hyperuricemia was defined as SUA level > 7.7 mg/dl in men or > 6.6 mg/dl in women. Kidney ...
2009 OCT 5 ... toward novel potential targets for pharmacological intervention to prevent or treat hyperuricemia," wrote M. Kolz and colleagues. The researchers concluded: "In addition, ...
2009 NOV 2 ... rheumatology section, The University of Chicago School of Medicine, gout associated with hyperuricemia is a chronic condition that requires long-term management. "One of the hallmarks of ...
