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2009 NOV 23 ... biomarker was discovered using Compugen's GeneVa® platform, which consists of an in silico database of approximately 350,000 predicted genetic variations in the human genome, with ...
2009 NOV 16 ... unknown splice variant was predicted and selected through the use of Compugen's in silico modeling of the human transcriptome and proteome for the discovery of novel molecules ...
2009 NOV 16 ... A new study, 'WEbcoli: an interactive and asynchronous web application for in silico design and analysis of genome-scale E.coli model,' is now available. According to a ...
2009 NOV 23 ... of these genes in vitro," researchers in Germany report. "According to in silico analysis, these mRNA regions possess distinct secondary structures sensitive to ...
2009 NOV 16 ... to Clinical Research programs development." About LIFE Biosystems LIFE Biosystems is an in silico discovery and clinical research consulting company focusing on the unmet therapeutic ...
2009 NOV 17 ... with in vitro experiments to reconstitute the behavior of these motile actin networks in silico using an Accumulative Particle-Spring (APS) model that builds on the Elastic Gel model, ...
2009 NOV 17 ... microRNA levels are dysregulated," scientists in Kanazawa, Japan report. "In silico analysis identified a potential miR-125b recognition element (MRE125b) in the ...
2009 NOV 23 ... Taylor and colleagues. The researchers concluded: "These results validate in silico screening as a robust approach to the discovery of inhibitors of this ...
2009 NOV 16 ... drugs. In this study, in vitro dissolution testing using biorelevant media coupled with in silico physiologically based pharmacokinetic (PBPK) modeling was applied to the prediction of ...
2009 NOV 16 ... of Structurally Diverse Antimalarial Drugs Targeting PfATP6: No Correlation between in silico Binding Affinity and in vitro Antimalarial Activity. Chemmedchem, 2009;4(9):1469-1479). ...
2009 NOV 23 ... crucial for promoter activity. Deletion and site-directed mutagenesis combined with in silico transcription factor binding analysis of VSNL1 promoter identified nuclear respiratory ...
2009 NOV 27 ... and colleagues published their study in Biochemistry - Moscow (In silico Analysis of Pectin Lyase and Pectinase Sequences. Biochemistry - Moscow, ...
2009 NOV 27 ... cells."Pieraccini and colleagues published their study in Nature Chemistry (In silico design of tubulin-targeted antimitotic peptides. Nature Chemistry, ...
2009 NOV 24 ... an opened conformation and fluctuates between three well-defined conductance states. In silico analysis of the EtpB amino acid sequence and molecular modeling suggest that EtpB is ...
2009 NOV 10 ... belongs to the T-box family of trunscription factors and was originally found using an in silico approach to identify new genes in the human Xq12-Xq21 region. Mutations in Thx22 have ...
2009 NOV 10 ... by direct sequencing in 130 Spanish patients from 115 unrelated families with FSGS. An in silico scoring matrix was developed to evaluate the pathogenicity of amino acid substitutions, ...
2009 NOV 17 ... of rice-sorghum synteny. The ESTs from which these markers were derived were then mapped in silico onto the aligned sorghum genome sequence, and 88% of the best hits corresponded to ...
2009 NOV 17 ... this study, methods for developing SNP markers in rapeseed (Brassica napus L.) and their in silico mapping and use for genotyping are demonstrated," scientists writing in the journal ...
