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2009 OCT 19 ... isolates, polymerase chain reaction was used to detect antibiotic resistance genes, integrase genes, and gene cassettes," scientists in Brno, Czech Republic report. ...
2009 NOV 16 ... from the United States, "We evaluated the human immunodeficiency virus type 1 (HIV-1) integrase coding region of the pol gene for the presence of natural polymorphisms in patients ...
2009 NOV 1 ... in the salvage regimen is often considered despite the risk of worsening resistance to integrase inhibitors," investigators in Paris, France report. "We determined ...
2009 NOV 29 ... HIV integration." For example, this mechanism might block the work of an enzyme called integrase, which is responsible for integrating the viral DNA into the DNA of the infected ...
Subject: Helmholtz Association of German Research Centres
2009 NOV 1 ... to a study from the United States, "LEDGF/p75 can tether over-expressed lentiviral integrase proteins to chromatin but how this underlies its integration cofactor role for these ...
2009 NOV 2 ... "The emergence of human immunodeficiency virus type 1 resistance to raltegravir, an integrase strand transfer inhibitor, follows distinct and independent genetic pathways, among ...
2009 NOV 2 ... luciferase was placed under the control of an UpsA var promoter. By utilising the Bxb1 integrase system, these reporter cassettes were targeted to a genomic region that was not in ...
2009 OCT 19 ... concluded: "Further, we have demonstrated the ubiquitous presence of the Tn916 integrase in the oral metagenomes and the Tn4451 and Tn1549...
2009 OCT 19 ... certain motifs are highly conserved." "We have examined the Ty1 integrase (IN) zinc binding domain by mutating the definitive histidine and cysteine residues and ...
2009 OCT 26 ... The researchers concluded: "The application of this method to crystals of lentiviral integrase in complex with its cofactor, where the observed translocation vector does not equal a ...
2009 NOV 9 ... in virus-like particles, and are associated with a dramatic decrease in the level of integrase, less reverse transcriptase, and an inability to synthesize Ty1 cDNA," wrote E. Matsuda ...
2009 OCT 26 ... "Experimental evidence suggests that a tetramer of integrase ( IN) is the protagonist of the concerted strand transfer reaction, whereby both ends of ...
2009 NOV 2 ... CGIN1 (Cousin of GIN1). CGIN1 proteins contain an NYN domain, retroviral RNase H and integrase domains, and a domain Of unknown function (CGIN1 domain) that is also present in two ...