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2009 JUL 13 ... to improve the binding of the active metabolite of the anti- inflammatory drug leflunomide to the target cavities of the P. falciparum and human dihydroorotate dehydrogenases. ...
2009 OCT 5 ... period for segments containing methotrexate (MTX), sulfasalazine, hydroxychloroquine and leflunomide was 28 (15-45), 12 (3-20), 18 (9-24), 15 (4-32) months. The log-rank statistical test ...
2009 JUN 29 ... of good clinical outcome in rheumatoid arthritis patients after one month therapy with leflunomide,' new data in arthritis. "This preliminary study focuses on early peripheral cellular ...
2009 AUG 3 ... efficacy/toxicity ratio than MTX alone with RR = 0.3 (95% CI 0.14 to 0.65). Adding leflunomide to MTX non-responders improved efficacy but increased the risk of gastrointestinal side ...
2009 MAY 18 ... BKV viruria. In a refractory thrombocytoponeic case, the add-on of anti-BKV medication, leflunomide 20mg/day rapidly decreased BKV viruria and recovered platelet counts," wrote M.C. Lu ...
2009 NOV 1 ... isolated from healthy donors and activated with IL-15 after exposure to different DMARD: leflunomide, cyclosporin A, methotrexate, mycophenolic acid, FK-506, sulphasalazine and sodium ...
2009 OCT 12 ... agents are nephrotoxic," scientists in Cologne, Germany report. "Leflunomide has immunosuppressive and antiviral properties and may be an alternative treatment ...
2009 SEP 28 ... Scientists discuss in 'Factors associated with fatal outcome of leflunomide-induced lung injury in Japanese patients with rheumatoid arthritis' new findings in ...
2009 NOV 3 ... Chikura and colleagues published their study in Rheumatology (Clinical expression of leflunomide-induced pneumonitis. Rheumatology, 2009;48(9):1065-1068). For more ...
2009 NOV 9 ... published study, investigators in Kuwait conducted a study "To assess the efficacy of leflunomide, intravenous immunoglobulins, and ciprofloxacin as active treatment of postrenal ...
2009 OCT 19 ... there is an association between CYP1A2*1F (-163C >A) allele and the risk for leflunomide-induced host toxicity. The *1F allele is associated with increased enzyme inducibility ...
2009 AUG 3 ... of China report. "Here we showed that A771726, the active metabolite of leflunomide, markedly enhanced tumor necrosis factor-related apoptosis-inducing ligand ...
2009 OCT 5 ... "To evaluate the clinical and pathological efficacy, and safety of leflunomide as a new immunosuppressive medicine in lupus nephritis (LN). A total of 31 patients were ...
