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2009 NOV 23 ... components of an effective vaccine must include antigens that are processed by the major histocompatibility complex class I pathway, presented by the tumor...
2009 NOV 11 ... models for biomedical research, necessitating a more extensive characterization of their major histocompatibility complex polymorphic regions. The current information on the polymorphism or diversity of the ...
2009 NOV 16 ... According to recent research from France, "Major histocompatibility complex antigens (MHC) are classical targets of recipient responses to allotransplants. However, ...
2009 NOV 16 ... immunity. We found that CSCs express high levels of tumor-associated antigens as well as major histocompatibility complex molecules. Furthermore, DC vaccination using CSC antigens elicited antigen-specific ...
2009 NOV 10 ... (TAP), which transports peptides into the endoplasmic reticulum (ER) for binding to major histocompatibility complex (MHC) class I molecules," scientists writing in the Journal of General Virology report. ...
2009 NOV 16 ... (AE) cells are known to have unique characteristics, such as low-level expression of major histocompatibility complex antigens and a less restricted differentiation potential. AE cells differentiate into ...
2009 NOV 23 ... examined islet cell status, including the presence of enterovirus and chemokine/cytokine/major histocompatibility complex (MHC) expressions in the pancreata using immunohistochemical analyses and RT-PCR. ...
2009 NOV 23 ... vivo' new findings in immunology. "Cross-presentation of soluble protein antigens on major histocompatibility complex (MHC) class I by dendritic cells (DC) can occur in vesicular, endolysosomal compartments ...
2009 NOV 10 ... of receptor-mediated sorting of lysosomal hydrolases. In contrast, downregulation of major histocompatibility complex (MHC) class I by HIV-1 Nef, which requires AP-1, was not affected by a triple GGA ...
2009 NOV 16 ... in FKBP5. Also less expressed in PTSD were STAT5B, a direct inhibitor of GR, and major histocompatibility complex (MHC) Class II," wrote R. Yehuda and colleagues. The researchers ...
2009 NOV 23 ... The majority of proliferating intimal cells are dendritic cells expressing CD11c and major histocompatibility complex class II and 33D1, but not CD11b. Systemic injection of granulocyte/macrophage ...
2009 NOV 16 ... in the journal Antioxidants & Redox Signaling, "Proper folding and assembly of major histocompatibility complex (MHC) class I complexes are essential for optimal peptide loading and subsequent antigen ...
2009 NOV 10 ... "Dendritic cells (DCs) express major histocompatibility complex class II (MHC II) to present peptide antigens to T cells. In immature DCs, which bear ...
2009 NOV 9 ... supports the CD226 gene as a susceptible candidate locus for type 1 diabetes outside the major histocompatibility complex region." Douroudis and colleagues published the results of their research ...
2009 NOV 23 ... report. "Neuro-2a cells were found to express low levels of class I major histocompatibility complex (MHC) antigens. While radiation and syngeneic bone marrow transplantation (BMT) reduced ...
2009 NOV 9 ... genetic risk factors for celiac disease are the DQ2 or DQ8 heterodimers at the major histocompatibility complex (MHC) class II locus (CELIAC1)." "These genes are necessary but alone not ...
2009 NOV 16 ... concluded: "Our findings suggest that the kinetic stability of complexes of peptide and major histocompatibility complex (MHC) is of importance for the association of HLA with disease." Fallang ...
2009 NOV 16 ... "A strong CTL response is dependent upon a high level of expression of specific class I major histocompatibility complex (MHC)/peptide complexes at the cell surface. An epitope-linked beta 2-microglobulin ...
2009 NOV 9 ... requires binding of the T cell receptor (TCR) to a complex between peptide antigen and major histocompatibility complex molecules (pMHC), and this recognition occurs at the interface between the T cell and ...
